Motor unit estimation: Anxieties and achievements

Motor unit estimation: Anxieties and achievements
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运动单位估计:焦虑和成就

DOI:
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发表时间:
1995
期刊:
影响因子:
3.4
通讯作者:
A. McComas
A. McComas
中科院分区:
医学3区
文献类型:
--
作者:
A. McComas

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运动单位数估计(MUNE)的历史,连同目前可用的各种方法的简要说明。手的一小块肌肉包含大约100个运动单位,在较大的肌肉中发现更多的运动单位;超过60岁,这些运动单位的数量开始下降。在ALS中,大约一半的运动单位在涉及运动神经元池的6个月内停止功能,而在成人脊髓性肌萎缩症中,几年内可能不会发生进一步的损失。强直性肌营养不良中MUNE值的降低仍然是一个谜,但更奇怪的是在甲状腺功能亢进和慢性肾功能衰竭中偶尔观察到的丢失和随后的恢复;可能涉及非传递(“沉默”)突触。MUNE也可用于研究中枢神经系统问题,如偏瘫和先天性臂麻痹。更强大的EMG计算机的可用性将导致MUNE的进步。John Wiley & Sons,Inc.
The history of motor unit number estimation (MUNE) is given, together with brief descriptions of the various methods presently available. A small muscle of the hand contains about 100 motor units and greater numbers are found in larger muscles; beyond 60 years the numbers begin to decline. In ALS approximately half the motor units cease to function within 6 months of the involvement of the motoneuron pool, while in adult spinal muscular atrophy further loss may not occur over several years. The reduction in MUNE values in myotonic dystrophy remains an enigma, but even more curious are the losses and subsequent recoveries occasionally observed in hyperthyroidism and chronic renal failure; possibly, nontransmitting (“silent”) synapses are involved. MUNE may also be used to study CNS problems such as hemiplegia and congenital brachial palsy. The availability of more powerful computers for EMG should lead to advances in MUNE. © 1995 John Wiley & Sons, Inc.
DOI: 10.1126/science.1546326
发表时间: 1992-03-06
期刊: SCIENCE
影响因子: 56.9
作者:
FU, YH;PIZZUTI, A;CASKEY, CT
通讯作者: CASKEY, CT