The Relations of Cognitive, Behavioral, and Physical Activity Variables to Depression Severity in Traumatic Brain Injury: Reanalysis of Data From a Randomized Controlled Trial.
The Relations of Cognitive, Behavioral, and Physical Activity Variables to Depression Severity in Traumatic Brain Injury: Reanalysis of Data From a Randomized Controlled Trial.
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DOI：
10.1097/htr.0000000000000288
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Temkin NR
中科院分区：
文献类型：
--
作者：
Bombardier CH;Fann JR;Ludman EJ;Vannoy SD;Dyer JR;Barber JK;Temkin NR
探讨接受抑郁治疗试验的创伤性脑损伤（TBI）患者的认知、行为和体力活动变量与抑郁严重程度的关系。社区成年人（N=88）在过去10年内持续复杂的轻度至重度TBI，符合重度抑郁症的标准，并完成了研究措施。随机对照试验参与者随机接受认知行为治疗（n=58）或常规护理（n=42）。在基线和16周时测量结果。我们将各组合并，并使用回归来探讨理论变量和抑郁症结果之间的关系。采用汉密尔顿抑郁评定量表和症状自评量表测量抑郁严重程度。基于理论的测量方法包括功能失调态度量表（DAS）、自动思维问卷（ATQ）、环境奖励观察量表（EROS）和国际身体活动问卷（IPAQ）。与非TBI标准相比，基线DAS和ATQ评分较高，EROS和IPAQ评分较低。除DAS外，所有结局均从基线至16周改善。ATQ是基线抑郁的独立预测因子。EROS评分的增加与抑郁症的减少相关。增加参与有意义的角色和愉快的活动可能是治疗TBI后抑郁症的一种有前途的方法。
To explore the relations of cognitive, behavioral, and physical activity variables to depression severity among people with traumatic brain injury (TBI) undergoing a depression treatment trial. Community Adults (N=88) who sustained complicated mild to severe TBI within the past 10 years, met criteria for major depressive disorder, and completed study measures. Randomized controlled trial Participants were randomized to cognitive-behavioral therapy (n=58) or usual care (n=42). Outcomes were measured at baseline and 16 weeks. We combined the groups and used regressions to explore the relations among theoretical variables and depression outcomes. Depression severity was measured with the Hamilton Depression Rating Scale and Symptom Checklist-20. Theory based measures were the Dysfunctional Attitudes Scale (DAS), Automatic Thoughts Questionnaire (ATQ), Environmental Rewards Observation Scale (EROS), and the International Physical Activity Questionnaire (IPAQ). Compared to non-TBI norms, baseline DAS and ATQ scores were high and EROS and IPAQ scores were low. All outcomes improved from baseline to 16 weeks except the DAS. The ATQ was an independent predictor of baseline depression. An increase in EROS scores was correlated with decreased depression. Increasing participation in meaningful roles and pleasant activities may be a promising approach to treating depression after TBI.