External Bone Size Is a Key Determinant of Strength-Decline Trajectories of Aging Male Radii
External Bone Size Is a Key Determinant of Strength-Decline Trajectories of Aging Male Radii
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DOI：
10.1002/jbmr.3661
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发表时间：
2019-05-01
影响因子：
6.2
通讯作者：
Jepsen, Karl J.
中科院分区：
文献类型：
--
作者：
Bigelow, Erin M. R.;Patton, Daniella M.;Jepsen, Karl J.
鉴于先前的研究表明重塑与外部骨骼尺寸之间存在关联，我们测试了以下假设：与窄骨相比，宽骨在全骨强度和年龄之间显示出更大的负相关性。对男性尸体桡骨（n = 37 对，18 至 89 岁）进行生物力学评估，并使用高度调整的稳健性（总面积/骨长度）将样本分为窄亚组和宽亚组。对于年轻人来说，宽半径的强度比窄半径的强度高 54% (p < 0.0001)
Given prior work showing associations between remodeling and external bone size, we tested the hypothesis that wide bones would show a greater negative correlation between whole-bone strength and age compared with narrow bones. Cadaveric male radii (n = 37 pairs, 18 to 89 years old) were evaluated biomechanically, and samples were sorted into narrow and wide subgroups using height-adjusted robustness (total area/bone length). Strength was 54% greater (p < 0.0001) in wide compared with narrow radii for young adults (