Comparison of various late gadolinium enhancement magnetic resonance imaging methods with high-definition voltage and activation mapping for detection of atrial cardiomyopathy
Comparison of various late gadolinium enhancement magnetic resonance imaging methods with high-definition voltage and activation mapping for detection of atrial cardiomyopathy
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DOI：
10.1093/europace/euac010
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发表时间：
2022-03-17
期刊：
影响因子：
6.1
通讯作者：
Jadidi, Amir
中科院分区：
文献类型：
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作者：
Eichenlaub, Martin;Mueller-Edenborn, Bjoern;Jadidi, Amir
心房心肌病（ACM）与肺静脉隔离（PVI）后心律失常复发率增加有关。我们比较了最常见的左心房（LA）晚期钆增强磁共振成像（LGE-MRI）方法[Utah方法和图像强度比（IIR）方法]和内膜电压标测用于房颤（AF）PVI后ACM检测和结局预测。方法和结果在这项前瞻性观察性研究中，37例消融初治的持续性AF患者（66 +/- 9岁，84%为男性）在肺静脉隔离前接受了窦性心律下的LA-LGE-MRI和高清电压和激动标测（2129 +/- 484个部位）。MRI后处理分析由两个独立的专家实验室进行。在肺静脉隔离后12个月内记录心律失常复发。总体ACM程度高度可变：中位LA低电压底物（LA-LVS）为12.9%，
Aims Atrial cardiomyopathy (ACM) is associated with increased arrhythmia recurrence rates after pulmonary vein isolation (PVI). We compare the most common left atrial (LA) late gadolinium enhancement magnetic resonance imaging (LGE-MRI)-methods [Utah-method and image intensity ratio (IIR)-methods] and endocardial voltage mapping for ACM-detection and outcome prediction after PVI for atrial fibrillation (AF). Methods and results In this prospective observational study, 37 ablation-naive patients (66 +/- 9 years, 84% male) with persistent AF underwent LA-LGE-MRI and high-definition voltage and activation mapping (2129 +/- 484 sites) in sinus rhythm prior to PVI. The MRI-post-processing-analyses were performed by two independent expert laboratories. Arrhythmia recurrence was recorded within 12 months following PVI. The global ACM-extent was highly variable: median LA low-voltage substrate (LA-LVS) was 12.9% at