Estradiol-17β-induced calcium uptake and resorption in juvenile rainbow trout, Oncorhynchus mykiss
Estradiol-17β-induced calcium uptake and resorption in juvenile rainbow trout, Oncorhynchus mykiss
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雌二醇-17β诱导虹鳟幼鱼的钙吸收和吸收
DOI：
10.1007/bf00003417
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发表时间：
1994
影响因子：
2.9
通讯作者：
B. Björnsson
中科院分区：
文献类型：
--
作者：
P. Persson;K. Sundell;B. Björnsson
以虹鳟（Oncorhynchus mykiss）幼鱼为材料，研究了雌激素（E2）对卵黄发生过程中所需钙的影响。E2处理增加了钙从外部介质的吸收，以及从肌肉和鳞片的钙动员。通过血浆蛋白结合钙水平的增加来判断，E2诱导的钙摄取增加是钙的明显过度动员，即，鱼的钙摄取量超过发现与血浆蛋白结合的量。由于钙排泄和钙空间（根据游离血浆钙水平计算）不受影响，因此建议将多余的钙纳入内部钙储存中。这意味着调节卵黄发生和钙平衡的系统是在机械或内分泌水平上整合的，并且E2引起钙动员的大小适合性成熟女性的需要。
Juvenile rainbow trout,Oncorhynchus mykiss, were injected with estradiol-17β (E2) in order to study the source of extra calcium needed during vitellogenesis. E2-treatment increased the calcium uptake from the external medium as well as calcium mobilization from muscle and scale. Judged by the increase in plasma protein-bound calcium levels, the E2-induced increase in calcium uptake is an apparent over-mobilization of calcium,i.e., the calcium uptake of the fish is in excess of what is found bound to plasma proteins. As the calcium excretion and calcium space (calculated from free plasma calcium levels) were unaffected, the excess calcium is suggested to be incorporated into internal calcium stores. This implies that the systems regulating vitellogenesis and calcium balance are integrated on the mechanistic or endocrine level, and that E2causes calcium mobilization of a magnitude geared to the needs of the sexually maturing female.