Sarcopenic obesity is associated with osteopenia among Japanese elderly women: A cross-sectional study from comprehensive health checkups
Sarcopenic obesity is associated with osteopenia among Japanese elderly women: A cross-sectional study from comprehensive health checkups
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肌肉减少性肥胖与日本老年女性骨质减少有关：综合健康检查的横断面研究
DOI：
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发表时间：
2018
期刊：
影响因子：
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通讯作者：
Y. Iwao
中科院分区：
文献类型：
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作者：
M. Takayama;K. Azuma;R. Shimizu;K. Makino;Takashi Seino;Toshifumi Yoshida;K. Kashiwagi;H. Hirose;N. Inoue;Y. Iwao
日本被称为超级老龄化社会，老年人口比例高达26.7%，2015年平均预期寿命达到男性80.75岁，女性86.99岁。在这种情况下，医疗服务和长期护理保险等社会保障福利的负担正在增加。因此，个人保持健康和避免老年残疾对国家利益至关重要。根据内阁办公室的年度报告，虚弱和骨关节病，如骨关节炎、骨质疏松症和骨折，是残疾的主要原因，特别是对老年妇女而言。因此，毫无疑问，保持一个人的运动器官功能是确保老年自主性的关键策略。衰老是运动功能恶化的主要危险因素。在衰老过程中出现的肌肉质量和功能的丧失被称为肌肉减少症，而获得脂肪质量会导致肥胖。异位脂肪的积累，如内脏脂肪组织，是老年人的一个特别显著的特征。近年来，肌肉减少症和肥胖症的共存，一种被称为肌肉减少性肥胖症（SO）的疾病，已经受到研究人员的关注，因为它不仅对功能下降，而且对心血管疾病，代谢紊乱和死亡率的患病率产生强烈影响。骨质减少是另一种随着年龄增长而发生的身体成分变化。骨量峰值一般在20多岁时形成，并一直维持到40多岁，之后逐渐下降。绝经会导致骨密度（BMD）急剧下降，因此绝经后女性比绝经前女性和男性更容易患骨质疏松症。最近一项针对日本人骨和关节疾病的人群流行病学研究显示，日本年龄≥ 40岁的成年人骨质疏松症的患病率
Japan is known as a super-aged society, with an elderly population ratio of 26.7%, and the average life expectancy reached 80.75 years for men and 86.99 years for women in 2015 . Under these circumstances, the burden of benefits of social security, such as medical service and long-term care insurance, is increasing. Therefore, it is vitally important to the national interest for individuals to maintain good health and avoid disability in their old age. According to the annual report of the Cabinet Office, frailty and osteoarthropathy, such as osteoarthritis, osteoporosis, and fracture, are major causes of disability, especially for elderly women. Thus, there is no doubt that maintaining one’s locomotive organ function is a pivotal strategy for ensuring autonomy in old age. Aging is a dominant risk factor for a deteriorated locomotive function. The loss of muscle mass and function that emerges during the aging process is known as sarcopenia, and gaining fat mass leads to obesity. The accumulation of ectopic fat, such as in visceral fat tissue, is a particularly distinctive feature of the elderly. Recently, the coexistence of sarcopenia and obesity, a condition known as sarcopenic obesity (SO), has received focus among researchers because of its strong impact on not only the functional decline but also the prevalence of cardiovascular disease, metabolic disorders , and mortality. Osteopenia is another body compositional change that occurs with age. The peak bone mass has generally been developed by one’s 20s and is maintained until one’s 40s, after which it gradually declines. Menopause causes a steep decline in the bone mineral density (BMD), so postmenopausal women are more vulnerable than premenopausal women and men to developing osteoporosis. A recent population-based epidemiological study for bone and joint diseases among the Japanese revealed that the prevalence of osteoporosis among Japanese adults ≥40 of age ORIGINAL ARTICLES
肌肉减少症、肥胖和炎症——血管紧张素转换酶抑制试验和新型心血管危险因素研究的结果。
DOI：
10.1093/ajcn.82.2.428
发表时间：
2005
期刊：
The American journal of clinical nutrition
影响因子：
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作者：
Cesari,Matteo;Kritchevsky,StephenB;Baumgartner,RichardN;Atkinson,HalH;Penninx,BrendaWHJ;Lenchik,Leon;Palla,ShanaL;Ambrosius,WalterT;Tracy,RussellP;Pahor,Marco
通讯作者：
Pahor,Marco