Burden of osteoporosis in adults in Korea: a national health insurance database study
Burden of osteoporosis in adults in Korea: a national health insurance database study
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DOI：
10.1007/s00774-011-0280-x
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发表时间：
2012-01-01
影响因子：
3.3
通讯作者：
Lee, Seong-Su
中科院分区：
文献类型：
--
作者：
Choi, Hyung Jin;Shin, Chan Soo;Lee, Seong-Su
我们评估了韩国2005-2008年接受治疗的骨质疏松症患者数量和长期趋势。我们使用健康保险审查机构（HIRA）的数据调查了韩国接受治疗的骨质疏松症患者人数的全国数据，其中包括全国范围的信息。对HIRA数据库2004年1月1日至2008年12月31日期间的报销记录进行了调查。根据研究定义的算法，使用处方数据和诊断代码，确定30岁骨质疏松症患者的年龄为千分之一。在研究期间，接受骨质疏松症相关治疗的女性患者人数从1，034，399人增加到1，392，189人，男性从120，496人增加到171，902人。在50岁以上的一般人群中，接受治疗的骨质疏松症患者的计算比例为男性6.1%，女性33.3%，在30岁以上的一般人群中，男性2.7%，女性16.6%。超过40%的患者（59.1%的女性; 41.2%的男性）接受了仅适用于骨质疏松症的药物治疗。约4-7%的骨质疏松症患者有既往病史，提示骨质疏松症的次要原因。超过80%的骨质疏松症患者是50岁以上的女性，反映了绝经后女性骨质疏松症的明显负担。这项研究表明，2005-2008年韩国成年人中与骨质疏松症相关的医疗索赔呈大幅增加趋势，绝经后妇女中骨质疏松症的负担明显加重。
We evaluated the number of osteoporosis patients under treatment and secular trends in 2005-2008 in South Korea. We investigated nationwide data regarding the number of osteoporosis patients under treatment in South Korea using data from the Health Insurance Review Agency (HIRA), which includes nationwide information. Reimbursement records from the HIRA database between 1 January 2004 and 31 December 2008 were investigated. Patients aged a parts per thousand yen30 years old with osteoporosis were identified based on a study-defined algorithm using prescription data and diagnostic codes. During the study periods, the number of patients receiving medical treatment related to osteoporosis increased from 1,034,399 to 1,392,189 for women and from 120,496 to 171,902 for men. The calculated proportion of osteoporosis patients under treatment in the general population over 50 years of age was 6.1% for men and 33.3% for women, and in the general population over 30 years of age was 2.7% for men and 16.6% for woman. More than 40% of patients (59.1% for women; 41.2% for men) were treated with medication indicated only for osteoporosis. About 4-7% of osteoporosis patients had a past medical history suggesting a secondary cause of osteoporosis. More than 80% of all osteoporosis patients were women older than 50 years, reflecting the pronounced burden of osteoporosis among postmenopausal women. This study demonstrated a substantial increasing trend in medical claims related to osteoporosis in 2005-2008 among adults in Korea and a pronounced burden of osteoporosis among postmenopausal women.