Proton computed tomography: Update on current status
Proton computed tomography: Update on current status
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质子计算机断层扫描：当前状态更新
DOI：
10.1109/nssmic.2007.4437152
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发表时间：
2007
期刊：
影响因子：
--
通讯作者：
A. Rosenfeld
中科院分区：
文献类型：
--
作者：
V. Bashkirov;R. Schulte;S. Penfold;A. Rosenfeld
质子束由于其物理特性而在放射治疗中提供高度的3D保形性。对于治疗计划和图像引导的放射治疗，质子也可以用于提供所需的电子密度和解剖信息。质子成像的一个优点是它可以利用来自穿过物体的每个单独质子的数据，使其非常有效。在过去的几年里，我们已经投入了相当大的努力，概念，理论和实验研究的质子计算机断层扫描（pCT）。在这篇文章中，我们将对这些研究的结果和pCT项目的现状进行更新。特别是，一个原型pCT设置包括一个硅微带跟踪器和碘化铯量热计安装在一个研究束线的洛马琳达医疗中心临床质子加速器将被描述和第一次获得的结果与此原型100 MeV的质子束。新一代pCT扫描仪的额外利用在线质子剂量验证和肿瘤成像与正电子发射断层扫描（PET）的建议。
Proton beams offer a high degree of 3D conformality in radiation therapy due to their physical characteristics. For treatment planning and image-guided radiation therapy, protons may also be used to provide the required electron density and anatomic information. One advantage of proton imaging is that it can utilize data from each individual proton that traverses the object making it very-dose efficient. Over the last few years, we have invested considerable efforts into conceptual, theoretical, and experimental studies of proton computed tomography (pCT). In this contribution, we will give an update on the outcomes of these studies and the current status of the pCT project. In particular, a prototype pCT setup consisting of a silicon microstrip tracker and cesium iodide calorimeter installed on one of research beam lines of the Loma Linda Medical Center clinical proton accelerator will be described and first results obtained with this prototype with a 100-MeV proton beam will be presented. The additional utilization of new-generation pCT scanners for on-line proton dose verification and tumor imaging with positron emission tomography (PET) is suggested.
影响因子：
3.8
作者：
Li, TF;Liang, ZR;Schulte, RW
通讯作者：
Schulte, RW