STRUCTURE OF SYRINGOTOXIN, A BIOACTIVE METABOLITE OF PSEUDOMONAS-SYRINGAE PV SYRINGAE
STRUCTURE OF SYRINGOTOXIN, A BIOACTIVE METABOLITE OF PSEUDOMONAS-SYRINGAE PV SYRINGAE
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DOI：
10.1016/0014-5793(90)81197-v
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发表时间：
1990-09-03
期刊：
影响因子：
3.5
通讯作者：
SIMMACO, M
中科院分区：
文献类型：
--
作者：
BALLIO, A;BOSSA, F;SIMMACO, M
根据1D和2D 1H-和13 C-NMR谱，结合大量的FAB-MS数据和一些化学反应的结果，推测了柑橘假单胞菌（Pseudomonaseringaepv. acringae）分离物的活性代谢产物--柑橘毒素的共价结构。与其它植物病原菌P.黄喉盘病毒，黄喉盘病毒毒素是一种脂缩芥子肽。其肽部分对应于Ser-Dab-Gly-Hse-Om-aThr-Dhb-（3-OH）Asp-（4-Cl）Thr，末端羧基封闭N-末端Ser的OH基团上的大环，其继而被3-羟基十四烷酸N-乙酰化。
The covalent structure of syringotoxin, a bioactive metabolite ofPseudomonas syringaepv.syringaeisolates, pathogenic on various species of citrus trees, has been deduced from ID and 2D1H- and13C-NMR spectra combined with extensive FAB-MS data and results of some chemical reactions. Similarly to syringomicins and syringostatins, produced by other plant pathogenic strains ofP. syringaepv.syringae, syringotoxin is a lipodep-sinonapeptide. Its peptide moiety corresponds to Ser-Dab-Gly-Hse-Om-aThr-Dhb-(3-OH)Asp-(4-Cl)Thr with the terminal carboxy group closing a macrocyclic ring on the OH group of the N-terminal Ser, which in turn is N-acetylated by 3-hydroxytetradecanoic acid.