Modulatory actions of octopamine and serotonin on the contraction of buccal muscles in Rapana thomasiana--I. Enhancement of contraction in radula protractor.
Modulatory actions of octopamine and serotonin on the contraction of buccal muscles in Rapana thomasiana--I. Enhancement of contraction in radula protractor.
复制标题
章鱼胺和血清素对 Rapana thomasiana 颊肌收缩的调节作用--I。
DOI：
10.1016/0306-4492(80)90024-6
复制
发表时间：
1980
期刊：
影响因子：
--
通讯作者：
Y. Muneoka
中科院分区：
文献类型：
--
作者：
M. Kobayashi;Y. Muneoka
1. L-谷氨酸和乙酰胆碱引起的收缩齿舌牵开器的红螺和高浓度的谷氨酸诱导更大的张力比乙酰胆碱。2. 2.高Mg ~（2+）可阻断抽搐收缩，箭毒可抑制抽搐收缩，但艾司洛尔不增强抽搐收缩。3. 3.章鱼胺和5-羟色胺使肌纤维膜超极化并抑制兴奋性连接电位。这些胺也抑制了抽搐收缩和低浓度谷氨酸引起的收缩。低浓度乙酰胆碱引起的收缩被5-羟色胺抑制，而被章鱼胺增强。4. 4.牵开器的提取物可缓解贻贝ABRM的抓持张力。mersalyl和氟哌啶醇都不能阻断这种松弛作用。5. 5.在牵开器中，L-谷氨酸可能是兴奋性递质，章鱼胺和5-羟色胺可能是抑制性递质。
1. L-Glutamate and acetylcholine evoked contraction in the radula retractor of Rapana thomasiana and at high concentrations glutamate induced larger tension than acetylcholine. 2. 2. Twitch contraction was blocked by high-Mg2+, depressed by curare but not potentiated by eserine. 3. 3. Octopamine and serotonin hyperpolarized muscle fibre membrane and depressed excitatory junctional pot potential. These amines also depressed twitch contraction and contraction by low concentration of glutamate. The contraction by low concentration of acetylcholine was depressed by serotonin but enhanced by octopamine. 4. 4. The extract of retractor relaxed catch tension in the Mytilus ABRM. Neither mersalyl nor haloperidol blocked the relaxation. 5. 5. In the retractor, L-glutamate may be an excitatory transmitter and octopamine and serotonin may be inhibitory transmitters.