Transition metal-catalyzed C-C bond formation reactions using alkyl halides
Transition metal-catalyzed C-C bond formation reactions using alkyl halides
复制标题
DOI：
10.1246/bcsj.79.663
复制
发表时间：
2006-05-15
影响因子：
4
通讯作者：
Kambe, Nobuaki
中科院分区：
文献类型：
--
作者：
Terao, Jun;Kambe, Nobuaki
本文回顾了使用烷基卤化物的过渡金属催化的 C-C 键形成反应，这些烷基卤化物很少在传统的过渡金属催化体系中用作碳源。在反应中，过渡金属与格氏试剂反应形成的配合物作为活性催化物种发挥着重要作用。这里提到的反应在机理上是新的，并为使用烷基卤化物构建碳骨架提供了一种有前途的方法。
This account reviews transition metal-catalyzed C-C bond formation reactions using alkyl halides, which have rarely been used as carbon sources in conventional transition metal-catalyzed systems. In the reactions, ate complexes formed by the reaction of transition metals with a Grignard reagent play important roles as the active catalytic species. The reactions mentioned here are mechanistically new and provide a promising methodology for the construction of carbon frameworks employing alkyl halides.