An outbreak of acute respiratory disease caused by Mycoplasma pneumoniae and adenovirus at a federal service training academy:: New implications from an old scenario
An outbreak of acute respiratory disease caused by Mycoplasma pneumoniae and adenovirus at a federal service training academy:: New implications from an old scenario
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DOI：
10.1086/313500
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发表时间：
1999-12-01
影响因子：
11.8
通讯作者：
Cetron, MS
中科院分区：
文献类型：
--
作者：
Feikin, DR;Moroney, JF;Cetron, MS
肺炎支原体和腺病毒的爆发已经在军事机构报道了几十年。在联邦服务培训学院最近的一次疫情中，我们进行了流行病学和实验室调查，以更好地描述和控制疫情。在回答问卷的586名学生中，317名（54%）报告在疫情爆发期间患有呼吸道疾病，在42名接受完整实验室检测的学生中，24名（57%）有肺炎支气管炎感染的证据，8名（19%）有腺病毒感染的证据，4名（10%）有两者的证据。口咽拭子聚合酶链反应检测显示急性肺炎支原体感染（57%阳性）多于血清学或培养。多变量分析显示，在疫情爆发初期，因非呼吸系统疾病（如受伤）到校园健康诊所就诊3次是新生患病的重要危险因素，而在整个疫情爆发期间，有生病的室友是一个危险因素。
Outbreaks of Mycoplasma pneumoniae and adenovirus have been reported in military institutions for several decades. During a recent outbreak in a federal service training academy, we performed an epidemiological and laboratory investigation to better characterize and control the outbreak, Of 586 students responding to a questionnaire, 317 (54%) reported having a respiratory illness during the outbreak period, Among 42 students who underwent complete laboratory testing, 24 (57%) had evidence of M. pneumoniae infection, 8 (19%) had evidence of adenovirus infection, and 4 (10%) had evidence of both. Polymerase chain reaction testing of oropharyngeal swabs revealed more acute M. pneumoniae infections (57% positive) than did serology or culture. Multivariate analysis revealed that visiting the campus health clinic >3 times for a nonrespiratory condition, such as injury, was a significant risk factor for illness among freshmen early in the course of the outbreak, whereas having an ill roommate was a risk factor throughout the duration of the outbreak.