A Practical and Chemoselective Ammonia-Free Birch Reduction
A Practical and Chemoselective Ammonia-Free Birch Reduction
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DOI：
10.1021/acs.orglett.8b00891
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发表时间：
2018-06-15
期刊：
影响因子：
5.2
通讯作者：
An, Jie
中科院分区：
文献类型：
--
作者：
Lei, Peng;Ding, Yuxuan;An, Jie
报道了一种新的由实验室稳定的钠分散体和可回收的15-冠-5醚介导的显着改进的、实用的和化学选择性的无氨Birch还原的方案。广泛的芳香族和杂芳香族化合物被还原，产率优异。
A novel protocol for a significantly improved, practical, and chemoselective ammonia-free Birch reduction mediated by bench-stable sodium dispersions and recoverable 15-crown-5 ether is reported. A broad range of aromatic and heteroaromatic compounds is reduced with excellent yields.