Cue-provoked craving and nicotine replacement therapy in smoking cessation
Cue-provoked craving and nicotine replacement therapy in smoking cessation
复制标题
DOI：
10.1037/0022-006x.72.6.1136
复制
发表时间：
2004-12-01
影响因子：
5.9
通讯作者：
Balabanis, MH
中科院分区：
文献类型：
--
作者：
Waters, AJ;Shiffman, S;Balabanis, MH
线索暴露范例已被用于检查吸烟线索的反应。然而，目前尚不清楚线索引发的渴望是否与吸烟，戒烟结果或线索反应是否可以通过尼古丁替代疗法（NRT）在临床样本中减弱。在戒烟的第一天，对158名随机接受高剂量尼古丁（35 mg）或安慰剂贴剂的吸烟者进行了线索诱发的渴望等级和反应时间反应的测量。尼古丁贴片降低了整体渴望水平，但没有减弱线索引起的渴望增加或反应时间反应。线索激发的渴望预测尼古丁贴片参与者的复发，而不是安慰剂参与者。总之，NRT使用者可以从减弱线索引起的渴望的治疗中受益。
Cue exposure paradigms have been used to examine reactivity to smoking cues. However, it is not known whether cue-provoked craving is associated with smoking, cessation outcomes or whether cue reactivity can be attenuated by nicotine replacement therapy (NRT) in clinical samples. Cue-provoked craving ratings and reaction time responses were measured on the 1 st day of abstinence among 158 smokers who had been randomized to high-dose nicotine (35 mg) or placebo patch. The nicotine patch reduced overall levels of craving but did not attenuate cue-provoked craving increases or reaction time responses. Cue-provoked craving predicted relapse among participants on the nicotine patch but not among those on placebo. In summary, NRT users could benefit from treatment that attenuates cue-provoked craving.