Regional differences in facial skin blood flow responses to the cold pressor and static handgrip tests
Regional differences in facial skin blood flow responses to the cold pressor and static handgrip tests
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DOI：
10.1007/s00421-012-2522-6
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发表时间：
2013-04-01
影响因子：
3
通讯作者：
Hayashi, Naoyuki
中科院分区：
文献类型：
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作者：
Kashima, Hideaki;Ikemura, Tsukasa;Hayashi, Naoyuki
我们之前已经报道了面部皮肤血流量(SkBF)对口服基本口味的独特区域反应，而没有同时发生全身循环变化。在本研究中，我们通过观察20名健康受试者面部对2分钟冷加压试验(CPT)和静态握手练习(HG)的面部SkBF和血压的反应，来确定交感神经激活引起的全身循环刺激是否会导致面部SkBF的区域性差异。与静息基线相比，CPT显著增加额部、眼皮、面颊、上唇和下唇的SkBF，增加6+/-A2~8+/-A2%(平均值+/-A)，同时显著增加平均动脉压(MAP)13+/-A2%，而显著降低鼻部SkBF 5+/-A2%。HG使额部、面颊和下唇的SkBF增加6+/-A3~10+/-A3%，MAP显著增加(13+/-A2%)，其他部位无明显变化。CPT期间右脸颊SkBF增加幅度大于左脸颊。这些结果表明，通过交感神经激活的全身循环刺激会引起面部SkBF反应的区域性差异。
We have previously reported the unique regional responses of facial skin blood flow (SkBF) to oral application of the basic tastes without simultaneous systemic circulatory changes. In the present study, we determined whether a systemic circulatory challenge due to sympathetic activation induces regional differences in facial SkBF by observing the responses in facial SkBF and blood pressure to a 2-min cold pressor test (CPT) and static handgrip exercise (HG) by right hand in 20 healthy subjects. The CPT significantly increased SkBF in the forehead, eyelid, cheek, upper lip and lower lip by 6 +/- A 2 to 8 +/- A 2 % (mean +/- A SEM) as compared to resting baseline, with a significant simultaneous increase (13 +/- A 2 %) in mean arterial pressure (MAP), whereas it significantly decreased the SkBF in the nose by 5 +/- A 2 %. The HG significantly increased SkBF in the forehead, cheek and lower lip by 6 +/- A 3 to 10 +/- A 3 %, with a significant simultaneous increase in MAP (13 +/- A 2 %), while it induced no significant change in the other regions. Increases in SkBF were greater in the right than left cheek during CPT. These results demonstrate that a systemic circulatory challenge via sympathetic activation elicits regional differences in the facial SkBF response.