CHANGES IN SLEEP CYCLE PATTERNS WITH AGE
CHANGES IN SLEEP CYCLE PATTERNS WITH AGE
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DOI：
10.1016/0022-3956(74)90011-9
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发表时间：
1974-01-01
影响因子：
4.8
通讯作者：
FEINBERG, I
中科院分区：
文献类型：
--
作者：
FEINBERG, I
通过睡眠周期对数据进行分析，以获得关于EEG慢波（SSW）睡眠、快速眼动睡眠和觉醒的主要变量。提供了6个年龄组的数据，平均年龄为7.4岁、13.8岁、21.6岁、31.5岁、55.3岁、77.3岁。虽然这些数据代表了第一个详细的统计描述周期变化与年龄，所获得的结果是一致的，与早期的观察。对于SSW，明显的年龄变化发生在第一个周期;所有6个年龄组的周期2-5的持续时间和变化率高度相似。第1周期随年龄的变化主要归因于第4阶段EEG随年龄的变化，除高龄组外，SREMP持续时间从第1周期到第3周期逐渐增加，之后变化不大。在老年受试者中，第一个SREMP的长度与后续周期相同。夜间眼动活动的趋势与SREMP持续时间的趋势相似;即，这些趋势表明，除年龄最大的组外，所有组从第一个周期到第三个周期都有增加。2这表明，夜间睡眠模式的趋势对睡眠电生理表现的大脑过程有重要意义。提出了一个推测性的假设，以解释睡眠的周期性、夜间周期的趋势以及年龄对这些变量的影响。该假说提出，快速眼动睡眠的功能是提供促进慢波睡眠最大发生所需的底物或辅因子。文献中的许多数据可以被视为与这一假设相一致。
An analysis of data by sleep cycle was carried out for the main variables concerning sleep with EEG slow waves (SSW), sleep with rapid eye movements, and awakenings. Data were presented for six age groups with mean ages of 7·4, 13·8, 21·6, 31·5, 55·3, 77·3 yr. While these data represent the first detailed statistical description of cycle changes with age, the results obtained are consistent with earlier observations. For SSW pronounced age changes occured in the first cycle; durations and rates of change across cycles 2–5 were highly similar for all six age groups. The changes with age in cycle 1 were attributed to the changing level of stage 4 EEG with age.Except for the oldest group, SREMP durations increased from cycle 1 to cycle 3, after which there was little change. In elderly subjects, the first SREMP was equal in length to succeeding periods. The trends across the night for eye movement activity were similar to those for SREMP duration; i.e., these trends showed increases from the first to third cycle for all groups except the oldest.It was suggested that the trends in sleep pattern across the night have significant implications for the brain processes which underlie the electrophysiological manifestations of sleep. A speculative hypothesis was advanced to account for the cyclical nature of sleep, the trends in cycles across the night, and the effects of age on these variables. This hypothesis proposes that the function of sleep with rapid eye movements is to provide a substrate or co-factor required to promote maximal occurrence of sleep with slow waves. Many data in the literature may be viewed as consistent with this hypothesis.