CELLULAR-LOCALIZATION OF SEROTONIN TRANSPORTER MESSENGER-RNA IN THE RAT-BRAIN
CELLULAR-LOCALIZATION OF SEROTONIN TRANSPORTER MESSENGER-RNA IN THE RAT-BRAIN
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DOI：
10.1016/0304-3940(93)90559-4
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发表时间：
1993-11-12
影响因子：
2.5
通讯作者：
TOHYAMA, M
中科院分区：
文献类型：
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作者：
FUJITA, M;SHIMADA, S;TOHYAMA, M
Expression of serotonin (5-hydroxytryptamine, 5-HT) transporter mRNA in the rat brain was examined by in situ hybridization histochemistry with a synthetic oligonucleotide probe. 5-HT transporter mRNA was expressed in neurons in most of the raphe nuclei. The dorsal and median raphe nuclei contained intensely labeled neurons, while the caudal linear nucleus, raphe magnus nucleus, raphe pontis nucleus, raphe pallidus nucleus and the raphe obscurus nucleus contained weakly or moderately labeled neurons. The localization pattern of the 5-HT transporter mRNA-positive neurons coincides fairly well with that of 5-HT-immunoreactive neurons, indicating that 5-HT transporter is primarily located in serotonergic neurons.
