Sphenoid esthesioneuroblastoma arising from the hindmost olfactory filament
Sphenoid esthesioneuroblastoma arising from the hindmost olfactory filament
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DOI：
10.1016/j.anl.2014.10.003
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发表时间：
2015-04-01
影响因子：
1.7
通讯作者：
Ito, Juichi
中科院分区：
文献类型：
--
作者：
Matsunaga, Mami;Nakagawa, Takayuki;Ito, Juichi
Esthesioneuroblastoma (ENB), or olfactory neuroblastoma, is a rare malignant neoplasm arising from the olfactory neuroepithelium. Typically, ENBs are found in the olfactory cleft with extension to the ethmoid sinuses or anterior skull base. Here we report a case of ENB located in the sphenoid sinus, which had been considered as an ectopic ENB. However, endoscopic resection revealed the continuity of the tumor with the hindmost olfactory filament. The present case suggests that an ENB in the sphenoid sinus was not ectopic, but arose from the normal olfactory neuroepithelium. This continuity of the ENB with this filament indicated that the tumor was not ectopic, and that there was possible tumor invasion into the olfactory neuroepithelium in the cribriform niche. Therefore, pathological examination of the olfactory neuroepithelium in the cribriform niche may be necessary in case of sphenoid ENBs. (C) 2014 Elsevier Ireland Ltd. All rights reserved.
