Neural responses to uninterrupted natural speech can be extracted with precise temporal resolution
Neural responses to uninterrupted natural speech can be extracted with precise temporal resolution
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DOI：
10.1111/j.1460-9568.2009.07055.x
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发表时间：
2010-01-01
影响因子：
3.4
通讯作者：
Foxe, John J.
中科院分区：
文献类型：
--
作者：
Lalor, Edmund C.;Foxe, John J.
人类的听觉系统已经进化到能够有效地处理单个的语言流。然而，迄今为止，使用标准的神经生理学技术来获得对不同连续的自然语音流的时间详细反应是不切实际的。这里描述了一种方法，该方法提供了对不间断自然语音的时间精确电生理反应的估计。我们把这种反应称为AESPA（听觉诱发扩频分析），它代表了听觉系统的脉冲反应的估计。它是通过假设记录的电生理功能表示连续语音流的幅度包络与待估计的脉冲响应的卷积而得到的。我们展示了这些反应的例子，使用头皮和颅内记录的人类脑电图，当受试者听双耳呈现的男性说话者自然朗读经典小说的录音时获得。这种方法扩展了刺激类型的武器库，现在可以有效地用于推导听觉诱发反应，并允许使用相当多的生态有效的刺激参数。对今后的研究工作提出了一些启示。
The human auditory system has evolved to efficiently process individual streams of speech. However, obtaining temporally detailed responses to distinct continuous natural speech streams has hitherto been impracticable using standard neurophysiological techniques. Here a method is described which provides for the estimation of a temporally precise electrophysiological response to uninterrupted natural speech. We have termed this response AESPA (Auditory Evoked Spread Spectrum Analysis) and it represents an estimate of the impulse response of the auditory system. It is obtained by assuming that the recorded electrophysiological function represents a convolution of the amplitude envelope of a continuous speech stream with the to-be-estimated impulse response. We present examples of these responses using both scalp and intracranially recorded human EEG, which were obtained while subjects listened to a binaurally presented recording of a male speaker reading naturally from a classic work of fiction. This method expands the arsenal of stimulation types that can now be effectively used to derive auditory evoked responses and allows for the use of considerably more ecologically valid stimulation parameters. Some implications for future research efforts are presented.