Synthesis of hexopyranosyl acetates and 2,3-disubstituted tetrahydropyrans via chemoselective hydrogenation of hex-2-enopyranosyl acetates
Synthesis of hexopyranosyl acetates and 2,3-disubstituted tetrahydropyrans via chemoselective hydrogenation of hex-2-enopyranosyl acetates
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DOI：
10.1016/j.tetlet.2006.09.091
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发表时间：
2006-11-20
影响因子：
1.8
通讯作者：
Toshima, Kazunobu
中科院分区：
文献类型：
--
作者：
Sasaki, Kaname;Wakamatsu, Takayuki;Toshima, Kazunobu
研究了以己-2-炔吡喃乙酸酯为原料，化学选择性合成己-炔吡喃乙酸酯和2,3-二取代四氢吡喃的简便方法。前者用Rh/Al2O3在EtOAc/甲苯溶剂中0℃催化加氢，后者用Pd/C在EtOH/AcOH溶剂中25℃催化加氢(C)。版权所有。
A simple and easy method for chemoselective synthesis of hexopyranosyl acetates and 2,3-disubstituted tetrahydropyrans from hex-2-enopyranosyl acetates was demonstrated. The former was achieved by hydrogenation catalyzed by Rh/Al2O3 in EtOAc/toluene solvent at 0 degrees C, while the latter was carried out using Pd/C in EtOH/AcOH at 25 degrees C. (c) 2006 Elsevier Ltd. All rights reserved.