AMPK and the Adaptation to Exercise.
AMPK and the Adaptation to Exercise.
复制标题
AMPK和适应运动。
DOI:
10.1146/annurev-physiol-060721-095517
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发表时间:
2022-02-10
影响因子:
18.2
通讯作者:
Yan Z
中科院分区:
文献类型:
--
作者:
Spaulding HR;Yan Z
Noncommunicable diseases are chronic diseases that contribute to death worldwide, but these diseases can be prevented and mitigated with regular exercise. Exercise activates signaling molecules and the transcriptional network to promote physiological adaptations, such as fiber type transformation, angiogenesis, and mitochondrial biogenesis. AMP-activated protein kinase (AMPK) is a master regulator that senses the energy state, promotes metabolism for glucose and fatty acid utilization, and mediates beneficial cellular adaptations in many vital tissues and organs. This review focuses on the current, integrative understanding of the role of exercise-induced activation of AMPK in the regulation of system metabolism and promotion of health benefits.
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影响因子:
4
作者:
Brandauer J;Andersen MA;Kellezi H;Risis S;Frøsig C;Vienberg SG;Treebak JT
通讯作者:
Treebak JT
DOI:
10.1073/pnas.2025932118
发表时间:
2021-09-14
影响因子:
11.1
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Yan Z
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4.8
作者:
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通讯作者:
Wojtaszewski, Jorgen F. P.
影响因子:
4.8
作者:
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通讯作者:
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7.7
作者:
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通讯作者:
Viollet, B