POLYPOIDAL CHOROIDAL VASCULOPATHY ASSOCIATED WITH CENTRAL SEROUS CHORIORETINOPATHY Pachychoroid Spectrum of Diseases
POLYPOIDAL CHOROIDAL VASCULOPATHY ASSOCIATED WITH CENTRAL SEROUS CHORIORETINOPATHY Pachychoroid Spectrum of Diseases
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DOI：
10.1097/iae.0000000000001665
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发表时间：
2018-06-01
影响因子：
3.3
通讯作者：
Narendran, Venkatapathy
中科院分区：
文献类型：
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作者：
Manayath, George J.;Shah, Vanee Sheth;Narendran, Venkatapathy
目的：目的：探讨息肉状脉络膜血管病变（PCV）合并中心性浆液性脉络膜视网膜病变（CSC）的多模式影像学特征，方法：对可疑PCV患者行吲哚菁绿色血管造影、荧光素眼底血管造影和光学相干断层扫描（OCT）检查，观察其在同一只眼同时出现典型CSC样活动性渗漏的情况。结果：226例患者中，195例有PCV，其中6例患眼有PCV，其余6例患眼有PCV，其中1例患眼有PCV，另1例患眼有PCV，其中1例患眼有PCV，另1例患眼有PCV，其中1例患眼有PCV，另1例患眼有PCV，其中1例患眼有PCV，另1例患眼有PCV，另1例患眼有PCV（3.07%）例患者的PCV特征与同一只眼睛中典型的CSC样活动性渗漏相关; 3例男性和3例女性，平均年龄为62.6岁。光学相干断层扫描显示缺口色素上皮脱离2例和不规则的高峰色素上皮脱离4例视网膜下液和/或视网膜下出血超过一个厚的脉络膜扩张脉络膜外血管。荧光素眼底血管造影显示息肉区有点状高荧光，3例有典型的CSC样活性渗漏墨点，3例有烟囱样渗漏墨点。吲哚菁绿色血管造影，多个息肉与脉络膜通透性过高，在后期的CSC leak.Conclusion网站：PCV与典型的CSC样活性泄漏和厚脉络膜在同一只眼睛的共存，同时提供了强有力的证据，这些疾病有关联，并支持这一假设，这些条件可能源于易感厚脉络膜。
Purpose: To study multimodal imaging features of polypoidal choroidal vasculopathy (PCV) associated with central serous chorioretinopathy (CSC) in the same eye.Methods: A retrospective observational study of cases of suspected PCV which underwent indocyanine green angiography, fundus fluorescein angiography and optical coherence tomography was done, to look for simultaneous typical CSC-like active leak in the same eye. The relevant history, best-corrected visual acuity, optical coherence tomography, fundus fluorescein angiography, and indocyanine green angiography findings were analyzed.Results: From 226 patients reviewed, 195 patients had PCV from which 6 eyes (3.07%) with features of PCV associated with typical CSC-like active leak in the same eye were identified; 3 men and 3 women with a mean age of 62.6 years. Optical coherence tomography showed notched pigment epithelial detachment in two and irregular peaked pigment epithelial detachment in four cases with subretinal fluid and/or subretinal haemorrhage over a thick choroid with dilated outer choroidal vessels. Fundus fluorescein angiography showed stippled hyperfluorescence at polyp area and a separate typical CSC-like active leak-Inkblot in three and Smokestack in three cases. On indocyanine green angiography, multiple polyps were noted with choroidal hyperpermeability in late phase at the site of CSC leak.Conclusion: The coexistence of PCV with typical CSC-like active leaks and a thick choroid in the same eye simultaneously provides strong evidence that these diseases have an association and support the hypothesis that these conditions may originate from predisposed thick choroid.