Mycoplasma pneumoniae infection & obsessive-compulsive disease:: A case report
Mycoplasma pneumoniae infection & obsessive-compulsive disease:: A case report
复制标题
DOI：
10.1177/0883073807308714
复制
发表时间：
2008-03-01
影响因子：
1.9
通讯作者：
Karasu, Gulten
中科院分区：
文献类型：
--
作者：
Ercan, Tugba Erener;Ercan, Gokmen;Karasu, Gulten
已经证明，儿童的强迫症和/或抽动综合征可能是由先前感染引发的，特别是A组β-溶血性链球菌，并且该亚组的儿童被命名为首字母缩写PANDAS（与链球菌感染相关的儿童自身免疫性神经精神障碍）。据报道，其他感染因子（如病毒和细菌）也与强迫症或图雷特综合征的急性发作或急剧恶化有关，另一个首字母缩略词PITAND（儿科感染引发的自身免疫性神经精神障碍）也出现在文献中。在单个病例报告中描述了其他感染因子（如肺炎支原体）的参与。我们描述了一个5.5岁的男孩谁突然发展成强迫症的症状，在一个M。肺炎口服克拉霉素治疗后，他的强迫症症状全部消失。据我们所知，这是第一个报告，表明肺炎支原体感染和强迫症之间的联系。
It has been demonstrated that obsessive-compulsive disease and/or tic syndromes in children may be triggered by an antecedent infection especially with group A beta-hemolytic streptococci, and this subgroup of children has been designated by the acronym PANDAS (pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections). Other infectious agents such as viruses and bacteria have also been reported to be associated with the acute onset or dramatic exacerbation of obsessive-compulsive disease or Tourette syndrome, and another acronym, PITAND (pediatric infection-triggered autoimmune neuropsychiatric disorder) has appeared in the literature. The involvement of other infectious agents such as Mycoplasma pneumoniae has been described in single case reports. We describe a case of a 5.5-year-old boy who suddenly developed obsessive-compulsive disease symptoms during a M. pneumoniae pneumonia. After treatment with oral clarithromycin, all his obsessive-compulsive disease symptoms disappeared. To our knowledge, this is the first report that shows the association between Mycoplasnw pneumoniae infection and obsessive-compulsive disease.