Improved Pediatric MR Imaging with Compressed Sensing
Improved Pediatric MR Imaging with Compressed Sensing
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DOI：
10.1148/radiol.10091218
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发表时间：
2010-08-01
期刊：
影响因子：
19.7
通讯作者：
Lustig, Michael
中科院分区：
文献类型：
--
作者：
Vasanawala, Shreyas S.;Alley, Marcus T.;Lustig, Michael
目的：开发一种结合并行成像和压缩传感的方法，以实现更快和/或更高空间分辨率的磁共振成像，并在儿科临床环境中展示其可行性。材料和方法：这项符合HIPAA标准的研究获得机构审查委员会的批准，受试者知情同意或同意。伪随机k空间欠采样图案被合并到三维(3D)梯度回波序列中；然后混叠具有非相干噪声样图案，而不是通常的相干折叠包裹图案。这种k空间采样模式与一种压缩感知非线性重建方法相结合，该方法利用医学图像的稀疏性假设，允许从欠采样的k空间数据中进行重建，并消除噪声混叠。34名患者(15名女性和19名男性；平均年龄8.1岁；范围0-17岁)接受了心血管、腹部和膝关节磁共振成像，在高加速因子下使用这种3D梯度回波序列进行扫描。利用传统的并行成像算法和非线性方法对得到的k空间数据进行重建。两组图像都由两位放射科医生根据图像质量、放射科医生的喜好和对特定结构的描述进行了评级。结果：与传统并行重建方法相比，压缩传感图像具有更高的图像质量评级，更高的图像质量评级和更好的解剖结构描述(P<；.001)。结论：并行成像和压缩传感相结合在临床上是可行的，可以提供更高的分辨率和/或更快的成像速度，解决了在儿科MR成像中描绘解剖结构的挑战。(C)RSNA，2010年
Purpose: To develop a method that combines parallel imaging and compressed sensing to enable faster and/or higher spatial resolution magnetic resonance (MR) imaging and show its feasibility in a pediatric clinical setting.Materials and Methods: Institutional review board approval was obtained for this HIPAA-compliant study, and informed consent or assent was given by subjects. A pseudorandom k-space undersampling pattern was incorporated into a three-dimensional (3D) gradient-echo sequence; aliasing then has an incoherent noiselike pattern rather than the usual coherent fold-over wrapping pattern. This k-space-sampling pattern was combined with a compressed sensing nonlinear reconstruction method that exploits the assumption of sparsity of medical images to permit reconstruction from undersampled k-space data and remove the noiselike aliasing. Thirty-four patients (15 female and 19 male patients; mean age, 8.1 years; range, 0-17 years) referred for cardiovascular, abdominal, and knee MR imaging were scanned with this 3D gradient-echo sequence at high acceleration factors. Obtained k-space data were reconstructed with both a traditional parallel imaging algorithm and the nonlinear method. Both sets of images were rated for image quality, radiologist preference, and delineation of specific structures by two radiologists. Wilcoxon and symmetry tests were performed to test the hypothesis that there was no significant difference in ratings for image quality, preference, and delineation of specific structures.Results: Compressed sensing images were preferred more often, had significantly higher image quality ratings, and greater delineation of anatomic structures (P < .001) than did images obtained with the traditional parallel reconstruction method.Conclusion: A combination of parallel imaging and compressed sensing is feasible in a clinical setting and may provide higher resolution and/or faster imaging, addressing the challenge of delineating anatomic structures in pediatric MR imaging. (C) RSNA, 2010