The developing intestinal microbiome and its relationship to health and disease in the neonate

The developing intestinal microbiome and its relationship to health and disease in the neonate
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DOI:
10.1038/jp.2010.172
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发表时间:
2011-04-01
影响因子:
2.9
通讯作者:
Neu, J.
Neu, J.
中科院分区:
医学3区
文献类型:
--
作者:
Torrazza, R. Murgas;Neu, J.

文献摘要

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肠道微生物群通常与宿主存在共生和/或共生关系。在过去的几年里,主要来自人类基因组计划的新兴技术已被应用于评估肠道微生物群,使用这些技术的新发现促使了新的举措,如人类微生物组路线图,旨在评估肠道微生物组在健康和疾病中的作用。在这篇综述中,我们希望关注这一领域的一些新进展,并讨论一些医疗操作,如抗生素,益生菌,益生元和剖腹产与阴道分娩对肠道微生物群的影响。围产期杂志(2011)31,S29-S34; doi:10.1038/jp.2010.172
The intestinal microbiota normally exists in a commensal and/or symbiotic relationship with the host. In the past few years, emerging technologies derived largely from the Human Genome Project have been applied to evaluating the intestinal microbiota and new discoveries using these techniques have prompted new initiatives such as the Human Microbiome Roadmap designed to evaluate the role of the intestinal microbiome in health and disease. In this review, we wish to focus on some new developments in this area and discuss some of the effects of medical manipulations such as antibiotics, probiotics, prebiotics and C-section versus vaginal delivery on the intestinal microbiota. Journal of Perinatology (2011) 31, S29-S34; doi: 10.1038/jp.2010.172