Genetic influences on frontal brain function: WCST performance in twins
Genetic influences on frontal brain function: WCST performance in twins
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DOI：
10.1097/00001756-200310270-00019
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发表时间：
2003-10-27
期刊：
影响因子：
1.7
通讯作者：
Ralano, A
中科院分区：
文献类型：
--
作者：
Anokhin, AP;Heath, AC;Ralano, A
威斯康星卡片分类测试（WCST）是最广泛使用的与前额皮质相关的执行功能评估之一。然而，人们对 WCST 表现个体差异的遗传和环境决定因素知之甚少。这项研究评估了 168 名年轻女性双胞胎样本中标准 WCST 分数的遗传力，其中包括 58 对同卵双胞胎和 25 对双卵双胞胎。几个 WSCT 指数，包括错误的数量和百分比、持续反应的数量以及持续错误的数量和百分比，显示出显着的遗传力，范围为 37% 至 46%。结果表明，WCST 测量的额叶执行功能的某些方面受到遗传因素的中等影响。
The Wisconsin Card Sorting Test (WCST) is one of the most widely used assessments of executive functioning related to prefrontal cortex. However, little is known about genetic and environmental determinants of individual differences in WCST performance. This study assessed heritability of standard WCST scores in a sample of 168 young female twins including 58 monozygotic and 25 dizygotic pairs. Several WSCT indices, including the number and percentage of errors, the number of perseverative responses, and the number and percent of perseverative errors, showed significant heritability ranging from 37 to 46%. The results suggest that selected aspects of frontal executive functioning measured by the WCST are moderately influenced by genetic factors.