BRAIN ANGIOTENSIN - RECEPTORS, ACTIONS AND POSSIBLE ROLE IN HYPERTENSION
BRAIN ANGIOTENSIN - RECEPTORS, ACTIONS AND POSSIBLE ROLE IN HYPERTENSION
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DOI：
10.1111/j.1600-0773.1992.tb01618.x
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发表时间：
1992-06-01
期刊：
影响因子：
--
通讯作者：
UNGER, T
中科院分区：
文献类型：
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作者：
STECKELINGS, UM;OBERMULLER, N;UNGER, T
脑是已经描述了内源性肾素血管紧张素系统（RAS）的器官之一（Ganten et al. 1984;坎贝尔1987）。刺激脑室周围或脑干血管紧张素I1（ANG 11）受体可产生不同的心血管、内分泌和行为反应模式，其特征为血压升高、压力感受器反射减弱、饮酒、尿钠排泄和垂体激素（如加压素、催产素和ACTH）释放（Unger et al. 1988）。
The brain is one of the organs where an intrinsic reninangiotensin system (RAS) has been described (Ganten et al. 1984; Campbell 1987). Stimulation of circumventricular or brainstem angiotensin I1 (ANG 11) receptors engenders a distinct pattern of cardiovascular, endocrine and behavioural responses featuring blood pressure increase, attenuation of the baroreceptor reflex, drinking, natriuresis, and release of pituitary hormones such as vasopressin, oxytocin and ACTH (Unger et al. 1988).