Spatiotemporal infectious disease modeling: a BME-SIR approach.
Spatiotemporal infectious disease modeling: a BME-SIR approach.
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DOI:
10.1371/journal.pone.0072168
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发表时间:
2013
期刊:
影响因子:
3.7
通讯作者:
Christakos G
中科院分区:
文献类型:
--
作者:
Angulo J;Yu HL;Langousis A;Kolovos A;Wang J;Madrid AE;Christakos G
This paper is concerned with the modeling of infectious disease spread in a composite space-time domain under conditions of uncertainty. We focus on stochastic modeling that accounts for basic mechanisms of disease distribution and multi-sourced in situ uncertainties. Starting from the general formulation of population migration dynamics and the specification of transmission and recovery rates, the model studies the functional formulation of the evolution of the fractions of susceptible-infected-recovered individuals. The suggested approach is capable of: a) modeling population dynamics within and across localities, b) integrating the disease representation (i.e. susceptible-infected-recovered individuals) with observation time series at different geographical locations and other sources of information (e.g. hard and soft data, empirical relationships, secondary information), and c) generating predictions of disease spread and associated parameters in real time, while considering model and observation uncertainties. Key aspects of the proposed approach are illustrated by means of simulations (i.e. synthetic studies), and a real-world application using hand-foot-mouth disease (HFMD) data from China.
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DOI:
10.1073/pnas.0600816103
发表时间:
2006-10-17
影响因子:
11.1
作者:
Elderd, Bret D.;Dukic, Vanja M.;Dwyer, Greg
通讯作者:
Dwyer, Greg
影响因子:
6.1
作者:
de Roos, AM;Leonardsson, K;Mittelbach, GG
通讯作者:
Mittelbach, GG
DOI:
10.1007/bf00890661
发表时间:
1990-10-01
期刊:
MATHEMATICAL GEOLOGY
影响因子:
--
作者:
CHRISTAKOS, G
通讯作者:
CHRISTAKOS, G
影响因子:
4.7
作者:
Christakos, G
通讯作者:
Christakos, G
影响因子:
4.3
作者:
Lloyd, AL;Jansen, VAA
通讯作者:
Jansen, VAA