DOUBLE-INTEGRATING-SPHERE SYSTEM FOR MEASURING THE OPTICAL-PROPERTIES OF TISSUE
DOUBLE-INTEGRATING-SPHERE SYSTEM FOR MEASURING THE OPTICAL-PROPERTIES OF TISSUE
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DOI：
10.1364/ao.32.000399
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发表时间：
1993-02-01
期刊：
影响因子：
1.9
通讯作者：
VANGEMERT, MJC
中科院分区：
文献类型：
--
作者：
PICKERING, JW;PRAHL, SA;VANGEMERT, MJC
描述并评价了一种同时测量组织的本征光学特性的系统：散射系数、吸收系数和各向异性因子。该系统综合了两个积分球和一个中间散射样品的理论，采用逆加倍算法，利用辐射传递方程的加倍解，通过测量每个球内的光通量和非散射透射来确定光学性质。光学性质可以同时测定，这样就可以在样品受热、化学变化或其他外部刺激时进行测量。实验结果表明，当光密度在1 ~ 10之间，反照率在0.4 ~ 0.95之间时，该系统的光学特性测定偏差小于5%。
A system is described and evaluated for the simultaneous measurement of the intrinsic optical properties of tissue: the scattering coefficient, the absorption coefficient, and the anisotropy factor. This system synthesizes the theory of two integrating spheres and an intervening scattering sample with the inverse adding-doubling algorithm, which employs the adding-doubling solution of the radiative transfer equation to determine the optical properties from the measurement of the light flux within each sphere and of the unscattered transmission. The optical properties may be determined simultaneously, which allows for measurements to be made while the sample undergoes heating, chemical change, or some other external stimulus. An experimental validation of the system with tissue phantoms resulted in the determination of the optical properties with a < 5% deviation when the optical density was between 1 and 10 and the albedo was between 0.4 and 0.95.