Reversed visuomotor behavior mediated by induced ipsilateral retinal projections in goldfish.
Reversed visuomotor behavior mediated by induced ipsilateral retinal projections in goldfish.
复制标题
金鱼诱导同侧视网膜投射介导的逆转视觉运动行为。
DOI：
--
复制
发表时间：
1977
影响因子：
2.5
通讯作者：
J. Schmidt
中科院分区：
文献类型：
--
作者：
S. Easter;J. Schmidt
1.当金鱼的一个视叶被切除，来自对侧眼睛的视神经被同侧偏转时，神经支配完整的、以前是外来的一侧。当对照眼保持完整时，动物表现出正常的游泳和头部与眼睛的协调。然而，在某些情况下，通过实验眼诱发的视动性眼震是反向的，表明功能性同侧投射明显超过游泳过程中的正常投射。2.当同样的手术过程伴随着对照眼的部分或完全破坏时，动物在同侧投射建立后不久就表现出明显的视觉行为逆转。它们会自发性地眼球震颤并不断地转圈。眼球震颤和旋转在完全黑暗中持续数天才消失。一旦动物回到阳光下，它们就会重新开始。3.前庭眼反射的偏置不同于正常，但增益的符号是正常的。4.我们的结论是，视觉的神经逆转引发了眼球震颤和转圈，并且视觉逆转的许多个月导致神经系统发生了一些更持久的变化，即使在没有即时视觉刺激的情况下，这些行为也会持续下去。
1. When one optic lobe of a goldfish is removed and the optic nerve from the contralateral eye is deflected ipsilaterally, the nerve innervates the intact, previously foreign side. When the control eye is left intact, the animal shows normal swimming and coordination of head and eyes. In some cases, however, optokinetic nystagmus evoked through the experimental eye is reversed, indicating a functional ipsilateral projection which was apparently outweighed by the normal projection during swimming. 2. When the same surgical procedure is accompanied by partial or complete destruction of the control eye, the animals show overt reversal of visuomotor behavior soon after the ipsilateral projection is established. They make a spontaneous nystagmus and circle continuously. The nystagmus and the circling persist in total darkness for days before they are extinguished. They resume as soon as the animal returns to light. 3. The vestibuloocular reflex is biased differently from normal, but the sign of the gain is normal. 4. We conclude that the neurological reversal of vision triggered the nystagmus and the circling, and that the many months with reversed vision resulted in some longer lasting change in the nervous system such that the behaviors persisted even in the absence of moment-to-moment visual stimulation.