Avoidant/Restrictive Food Intake Disorder Characteristics and Prevalence in Adult Celiac Disease Patients.
Avoidant/Restrictive Food Intake Disorder Characteristics and Prevalence in Adult Celiac Disease Patients.
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DOI：
10.1016/j.gastha.2022.01.002
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发表时间：
2022-01-01
期刊：
影响因子：
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通讯作者：
Adams, Dawn W
中科院分区：
文献类型：
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作者：
Bennett, Audrey;Bery, Alexandra;Adams, Dawn W
背景和目的：本研究的目的是了解乳糜泻(CD)患者中回避性/限制性食物摄入障碍(ARFID)的患病率，评估代谢并发症、疾病控制、饮食依从性以及与症状和生活质量指标的相关性。方法：对2018年至2020年在CD门诊完成ARFID调查的137名成年CD患者进行回顾性研究。回顾了人口学、临床结果、标准化饮食评估、腹泻病症状日记和无谷蛋白饮食调查问卷的结果。结果：78名患者(57%)符合疑似ARFID标准。患有或不患有ARFID的患者在年龄、性别、体重指数、微量营养素缺乏或骨骼疾病方面没有差异。与非ARFID患者相比，ARFID患者在活检活动或更好地坚持无麸质饮食方面没有差异。食物和社会负担对无麸质饮食问卷的影响对ARFID的预测作用最大。结论：ARFID在CD患者中很常见，影响很大。尽管一些饮食行为肯定是由于他们的CD，但在疑似ARFID患者和非ARFID患者之间，在疾病控制方面没有明显差异，这表明这些不适应行为对于疾病控制并不是必要的。我们没有发现代谢并发症增加，但这是两年的快照。我们需要进一步了解在这项调查中得分较高的患者的社会和食物影响，以防止进一步的缺陷和受损的长期有害饮食行为。
Background and Aims: The objective of this study was to identify the prevalence of avoidant/restrictive food intake disorder (ARFID) in patients with celiac disease (CD) and assess metabolic complications, disease control, diet adherence, and correlation with symptom and quality-of-life metrics.Methods: This was a retrospective study of 137 adult patients with CD who completed an ARFID survey in the CD clinic between 2018 and 2020. Demographics, clinical results, standardized diet assessment, and results of Celiac Disease Symptom Diary and Impact of a Gluten-free Diet Questionnaire were reviewed. The primary outcome measured was the rate of suspected ARFID based on patient-reported survey responses.Results: Seventy-eight patients (57%) met suspected ARFID criteria. There were no differences in age, gender, body mass index, micronutrient deficiencies, or bone disease in those with or without ARFID. Patients with ARFID did not have a difference in biopsy activity or better adherence to a gluten-free diet compared with non-ARFID patients. Food and social burden on Impact of a Gluten-free Diet Questionnaire was most predictive of ARFID.Conclusion: ARFID is common and has a high impact in patients with CD. Although some eating behavior is certainly due to their CD, there was no distinct difference in disease control between those with or without suspected ARFID, suggesting these maladaptive behaviors are not necessary for disease control. We did not find increased metabolic complications, but this was a 2-year snapshot. We need to further understand the social and food impacts on patients who score high on this survey to prevent further deficiencies and impaired, long-term detrimental eating behaviors.