Relations of left ventricular mass to demographic and hemodynamic variables in American Indians - The Strong Heart Study
Relations of left ventricular mass to demographic and hemodynamic variables in American Indians - The Strong Heart Study
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DOI：
10.1161/01.cir.96.5.1416
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发表时间：
1997-09-02
期刊：
影响因子：
37.8
通讯作者：
Howard, BV
中科院分区：
文献类型：
--
作者：
Devereux, RB;Roman, MJ;Howard, BV
背景 先前的研究已经确定了左心室 (LV) 质量与人口统计学（身体习惯和性别）和血流动力学变量（血压、每搏输出量 [SV] 和心肌收缩力）之间的关联，但这些关联的相对强度和独立性仍然未知。方法和结果我们检查了超声心动图确定的 LV 质量与人口统计学变量、血压、多普勒 SV 和收缩力测量（收缩末期压力 [ESS]/收缩末期容积指数和中壁）的关系。缩短分数 [MFS] 占 1935 年美国印第安人参加强心脏研究第 2 期检查时预测的周向收缩末期应力 [应力无关缩短] 的百分比，无二尖瓣反流或节段性心律异常。左心室质量与收缩压和舒张压（r=.22 和 r=.20）的弱正关系被与身高（r=.30）、体重（r=.47）、体重指数（r=.31）、体表面积（r=.49）和多普勒 SV（r=.50）的正关系以及与 ESS/体积指数比率（r=-.33 和 r=.33）的负关系所超越。 -.29) 和应力无关的 MFS (r=-.26, 所有 P
Background Previous studies have identified associations of left ventricular (LV) mass with demographic (body habitus and sex) and hemodynamic variables (blood pressure, stroke volume [SV], and myocardial contractility), but the relative strength and independence of these associations remain unknown.Methods and Results We examined the relations of echocardiographically determined LV mass to demographic variables, blood pressure, Doppler SV, and measures of contractility (end-systolic stress [ESS]/end-systolic volume index and mid-wall fractional shortening [MFS] as a percentage of predicted for circumferential end-systolic stress [stress-independent shortening]) in 1935 American Indian participants in the Strong Heart Study phase 2 examination without mitral regurgitation or segmental wail motion abnormalities. Weak positive relations of LV mass with systolic and diastolic pressures (r=.22, and r=.20) were exceeded by positive relations with height (r=.30), weight (r=.47), body mass index (r=.31), body surface area (r=.49), and Doppler SV (r=.50) and negative relations with ESS/volume index ratios (r=-.33 and -.29) and stress-independent MFS (r=-.26, all P