Clinical characteristics of congenital and developmental cataract undergoing surgical treatment
Clinical characteristics of congenital and developmental cataract undergoing surgical treatment
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DOI：
10.1007/s10384-015-0370-8
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发表时间：
2015-05-01
影响因子：
2.4
通讯作者：
Azuma, Noriyuki
中科院分区：
文献类型：
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作者：
Nagamoto, Toshiyuki;Oshika, Tetsuro;Azuma, Noriyuki
为分析先天性/发育性白内障手术患者的临床特点，对49家先天性/婴幼儿白内障手术治疗机构进行邮寄问卷调查，收集手术前临床特征资料，29家机构报告先天性/婴幼儿白内障患者521例864只眼，初诊年龄0~18.8岁(2.6+/-A 3.3岁，平均+/-A标准差)。双眼白内障占65.8%，单眼白内障占34.2%。有家族史者占22.4%，其中双侧占98.1%。家族史阳性的双侧病例占33.1%，单侧病例占1.3%。最常见的主诉是白瞳，双眼占35.7%，单眼占32.7%。伴有全身异常的双侧病例(31.6%)比单侧病例(16.7%)更常见。相关的眼部疾病，如斜视、持续性胎儿血管形成和后圆锥，多见于单眼，而眼球震颤多见于双眼。在先天性/发育性白内障中，双眼和单眼的比例约为2：1。几乎所有有先天性白内障家族史的患者都是双眼。初次看医生的时间相当晚，出生后2.6年；这一点应该得到改善。
To analyze the clinical characteristics of congenital/developmental cataract undergoing surgery.A mail questionnaire was sent to 49 facilities engaged in surgical treatment of congenital cataracts, and data on preoperative clinical features were collected.Twenty nine facilities reported on 864 eyes of 521 patients with congenital/infantile cataract, ranging in age at initial visit from 0 to 18.8 years (2.6 +/- A 3.3 years, mean +/- A standard deviation). Among the patients, 65.8 % had bilateral cataracts and 34.2 % were unilaterally affected. Family history was found for 22.4 % of cases, of which 98.1 % were bilateral. Family history was positive for 33.1 % of bilateral and 1.3 % of unilateral cases. The most common main complaint was white pupil for 35.7 % of bilateral cases and 32.7 % for unilateral cases. Concomitant systemic abnormalities were more frequently associated with bilateral cases (31.6 %) than with unilateral cases (16.7 %). Associated ocular diseases, such as strabismus, persistent fetal vasculature, and posterior lenticonus, were more frequently seen among unilateral cases whereas nystagmus was more common among bilateral cases.Among congenital/developmental cataracts, the ratio of bilateral and unilateral cases was approximately 2:1. Almost all patients with a family history of congenital cataract were bilateral. Initial visits to a physician were rather late, 2.6 years from birth; this should be improved.