Lithium Perchlorate Catalyzed Reactions of Indoles: An Expeditious Synthesis of Bis(indolyl)methanes
Lithium Perchlorate Catalyzed Reactions of Indoles: An Expeditious Synthesis of Bis(indolyl)methanes
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DOI：
10.1055/s-2001-12777
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发表时间：
2001
期刊：
影响因子：
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通讯作者：
J. Yadav;B. Reddy;C. Murthy;G. M. Kumar;C. Madan
中科院分区：
文献类型：
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作者：
J. Yadav;B. Reddy;C. Murthy;G. M. Kumar;C. Madan
高氯酸锂在乙醚中催化吲哚与醛、酮的亲电取代反应，产率高，生成吲哚基甲烷。LiOTf也被发现是合成这些化合物的有效催化剂。
Lithium perchlorate is found to catalyze efficiently the electrophilic substitution reactions of indoles with aldehydes and ketones in diethyl ether to afford the corresponding bis(indolyl)methanes in high yields. LiOTf is also found to be an efficient catalyst for the synthesis of these compounds.