Cavitation detection during shock-wave lithotripsy
Cavitation detection during shock-wave lithotripsy
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DOI：
10.1016/j.ultrasmedbio.2005.02.017
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发表时间：
2005-09-01
影响因子：
2.9
通讯作者：
Evan, AP
中科院分区：
文献类型：
--
作者：
Bailey, MR;Pishchalnikov, YA;Evan, AP
建立了一个系统，用于在使用Dornier HM 3碎石机进行冲击波碎石（SWL）期间检测猪肾中的空化。使用B型超声回波的主动检测和使用共焦正交接收器上的重合信号的被动空化检测被用于询问肾收集系统（尿液）和肾实质（组织）。在尿液或尿液加X射线造影剂中给予冲击波（SW）后立即在尿液中检测到空化，但在天然组织中，空化需要数百个SW才能启动。通过荧光透视、超声检查和使用被动空化检测接收器作为高强度聚焦超声源热标记肾脏来确认空化的定位。组织和天然尿液中的空化塌陷时间大致相同，但小于注射X射线造影剂后的尿液。肾组织中发生空化的发现是确定SWL中组织损伤机制的关键一步。（电子邮件：bailey@api.washington.edu）（c）2005年世界医学和生物学超声联合会。
A system was built to detect cavitation in pig kidney during shock-wave lithotripsy (SWL) with a Dornier HM3 lithotripter. Active detection using echo on B-mode ultrasound, and passive cavitation detection using coincident signals on confocal orthogonal receivers, were used to interrogate the renal collecting system (urine) and the kidney parenchyma (tissue). Cavitation was detected in urine immediately upon shock-wave (SW) administration in urine or urine plus X-ray contrast agent but, in native tissue, cavitation required hundreds of SWs to initiate. Localization of cavitation was confirmed by fluoroscopy, sonography and by thermally marking the kidney using the passive cavitation detection receivers as high-intensity focused ultrasound sources. Cavitation collapse times in tissue and native urine were about the same, but less than in urine after injection of X-ray contrast agent. The finding that cavitation occurs in kidney tissue is a critical step toward determining the mechanisms of tissue injury in SWL. (E-mail: bailey@api.washington.edu) (c) 2005 World Federation for Ultrasound in Medicine & Biology.