Mental health, substance use, and suicidal ideation during a prolonged COVID-19-related lockdown in a region with low SARS-CoV-2 prevalence.

Mental health, substance use, and suicidal ideation during a prolonged COVID-19-related lockdown in a region with low SARS-CoV-2 prevalence.
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DOI:
10.1016/j.jpsychires.2021.05.080
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发表时间:
2021-08
影响因子:
4.8
通讯作者:
Rajaratnam SMW
Rajaratnam SMW
中科院分区:
医学2区
文献类型:
--
作者:
Czeisler MÉ;Wiley JF;Facer-Childs ER;Robbins R;Weaver MD;Barger LK;Czeisler CA;Howard ME;Rajaratnam SMW

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由于直接(即SARS-CoV-2感染,可能是由于神经元或星形细胞感染、微血管或炎症机制)和间接(即COVID-19预防措施的社会和经济影响)影响,2019年冠状病毒病(COVID-19)大流行与精神健康后果有关。在全球封锁时间最长、COVID-19患病率最低的地区之一(澳大利亚维多利亚州)进行的心理健康调查,允许在没有重大直接大流行心理健康后果的情况下评估心理健康。2020年9月15日至24日,对年龄≥18岁的维多利亚州居民进行了2019冠状病毒病爆发公众评估(COPE)计划的调查。调查结果与2020年4月的数据进行了横向比较,并对完成这两项调查的受访者进行了纵向比较。使用多变量泊松回归来估计不良心理健康症状、药物使用和自杀意念的患病率,并根据人口统计学、睡眠和行为(如屏幕时间、户外时间)进行调整。2020年9月,在1157名维多利亚州人中,三分之一的人报告了焦虑或抑郁障碍症状,五分之一的人报告了自杀意念,十分之一的人报告在过去30天内认真考虑过自杀。年轻人、没有报酬的照料者、残疾人以及被诊断患有精神疾病或睡眠疾病的人出现不良心理健康症状的比例增加。2020年4月至2020年9月期间,倦怠、焦虑和抑郁障碍症状的患病率估计值没有变化。在长期封锁期间,尽管SARS-CoV-2的患病率较低,但不良心理健康症状的持续普遍经历,突显了对心理健康支持服务的迫切需要。
The coronavirus disease 2019 (COVID-19) pandemic has been associated with mental health consequences due to direct (i.e., SARS-CoV-2 infection, potentially due to neuronal or astrocytic infection, microvascular, or inflammatory mechanisms) and indirect (i.e., social and economic impacts of COVID-19 prevention measures) effects. Investigation of mental health in a region with one of the longest lockdowns and lowest COVID-19 prevalence globally (Victoria, Australia) allowed for evaluation of mental health in the absence of substantial direct pandemic mental health consequences. Surveys were administered during 15–24 September 2020 to Victorian residents aged ≥18 years for The COVID-19 Outbreak Public Evaluation (COPE) Initiative. Responses were compared cross-sectionally with April-2020 data, and longitudinally among respondents who completed both surveys. Multivariable Poisson regressions were used to estimate prevalence ratios for adverse mental health symptoms, substance use, and suicidal ideation adjusted for demographics, sleep, and behaviours (e.g., screen-time, outdoor-time). In September-2020, among 1157 Victorians, one-third reported anxiety or depressive disorder symptoms, one-fifth reported suicidal ideation, and one-tenth reported having seriously considered suicide in the prior 30 days. Young adults, unpaid caregivers, people with disabilities, and people with diagnosed psychiatric or sleep conditions showed increased prevalence of adverse mental health symptoms. Prevalence estimates of symptoms of burnout, anxiety, and depressive disorder were unchanged between April-2020 and September-2020. Persistently common experiences of adverse mental health symptoms despite low SARS-CoV-2 prevalence during prolonged lockdown highlight the urgent need for mental health support services.
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