THE STABILIZING SYSTEM OF THE SPINE .2. NEUTRAL ZONE AND INSTABILITY HYPOTHESIS
THE STABILIZING SYSTEM OF THE SPINE .2. NEUTRAL ZONE AND INSTABILITY HYPOTHESIS
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DOI：
10.1097/00002517-199212000-00002
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发表时间：
1992-12-01
期刊：
影响因子：
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通讯作者：
PANJABI, MM
中科院分区：
文献类型：
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作者：
PANJABI, MM
中立区是围绕中立姿势的椎间运动区域，其中被动脊柱提供的阻力很小。几项研究（体外尸体、体内动物和数学模拟）表明，中性区是一个与指示脊柱系统不稳定的其他参数密切相关的参数。人们发现，它会随着损伤而增加，并且可能会随着退化而增加，随着跨越水平的肌肉力量的增加而减少，并且也会随着仪器脊柱固定而减少。在大多数研究中，发现中立区的变化比相应运动范围的变化更敏感。中性区似乎是脊柱稳定性功能的临床重要测量指标。它可能会随着脊柱受伤或肌肉无力而增加，进而可能导致脊柱不稳定或腰部问题。通过骨赘形成、手术固定/融合和肌肉强化，它可能会减少，并可能会降至生理限度内。脊柱稳定系统进行调整，使中性区保持在一定的生理阈值内，以避免临床不稳定。
The neutral zone is a region of intervertebral motion around the neutral posture where little resistance is offered by the passive spinal column. Several studies-in vitro cadaveric, in vivo animal, and mathematical simulations-have shown that the neutral zone is a parameter that correlates well with other parameters indicative of instability of the spinal system. It has been found to increase with injury, and possibly with degeneration, to decrease with muscle force increase across the spanned level, and also to decrease with instrumented spinal fixation. In most of these studies, the change in the neutral zone was found to be more sensitive than the change in the corresponding range of motion. The neutral zone appears to be a clinically important measure of spinal stability function. It may increase with injury to the spinal column or with weakness of the muscles, which in turn may result in spinal instability or a low-back problem. It may decrease, and may be brought within the physiological limits, by osteophyte formation, surgical fixation/fusion, and muscle strengthening. The spinal stabilizing system adjusts so that the neutral zone remains within certain physiological thresholds to avoid clinical instability.