Vertebral measurements for assessment of osteoporosis.
Vertebral measurements for assessment of osteoporosis.
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DOI：
10.1259/0007-1285-67-800-759
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发表时间：
1994-08
期刊：
影响因子：
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通讯作者：
Masako Ito;Kuniaki Hayashi;M. Yamada;Toshikazu Nakamura
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文献类型：
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作者：
Masako Ito;Kuniaki Hayashi;M. Yamada;Toshikazu Nakamura
我们测量了健康女性的椎体高度和脊柱骨密度（BMD），并用形态计量学评估了椎骨的生理特征，以探讨骨密度与脊柱畸形类型的关系以及椎体骨密度降低的x线片检出率。使用双x线吸收仪测量245名年龄在22岁至81岁之间的健康女性从L1到L4的椎体骨密度，使用定量计算机断层扫描从L1到L3的骨密度。测量T12至L5椎体前高度（Ha）、中高度（Hm）和后高度（Hp），并计算Ha/Hp和Hm/Hp比值。尽管椎体高度随年龄的下降不如骨密度的下降明显，但椎体高度，尤其是T12至L5椎体的Ha和Hm，以及T12至L3椎体的Ha/Hp和Hm/Hp随年龄的增长而显著降低。楔形畸形与皮质骨密度密切相关，双凹畸形与小梁骨密度密切相关。尽管对几种标准的敏感性和特异性的研究表明，椎体特异性尺寸标准在检测骨密度降低方面是有用的，但使用椎体测量来检测骨密度降低被认为是有限的。
We measured the vertebral heights and spinal bone mineral density (BMD) of healthy women, and morphometrically evaluated the physiological features of the vertebrae to investigate the relationship of BMD to types of spinal deformity as well as the radiographic detection rate for decreased vertebral bone density. Vertebral BMD was measured from L1 to L4 using dual X-ray absorptiometry and from L1 to L3 using quantitative computed tomography in 245 healthy women ranging in age from 22 to 81 years. The vertebral heights, anterior (Ha), middle (Hm), and posterior (Hp), were measured from T12 through L5, and the Ha/Hp and Hm/Hp ratios were calculated. Although the age-related reduction of vertebral height was not as marked as that of BMD, the vertebral heights, especially the Ha and Hm from T12 to L5 vertebrae, and the Ha/Hp and Hm/Hp from T12 to L3, significantly decreased with age. The presence of a wedge-shaped deformity was strongly related to cortical BMD, and biconcave deformity to trabecular BMD. Although investigation of the sensitivity and specificity of several criteria revealed that vertebra-specific dimension criteria are useful in the detection of decreased bone density, the detection of decreased BMD using vertebral measurements is considered to be limited.