Japanese Legacy Cohort Studies: The Hisayama Study.

Japanese Legacy Cohort Studies: The Hisayama Study.
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日本遗产队列研究:Hisayama研究。

DOI:
10.2188/jea.je20180150
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发表时间:
2018-11-05
影响因子:
4.7
通讯作者:
Ninomiya T
Ninomiya T
中科院分区:
医学3区
文献类型:
--
作者:
Ninomiya T

文献摘要

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Hisayama研究是一项基于人群的前瞻性队列研究,旨在评价日本普通人群中生活方式相关疾病(如中风、冠心病、高血压、糖尿病和痴呆)的风险因素。自1961年以来,在40岁或以上的受试者中进行了前瞻性随访调查。这项研究的显著特点包括高参与率(所有40岁或以上居民的70-80%),高随访率(99%或以上)和高尸检率(约75%的死亡病例)。Hisayama研究提供了宝贵的证据,证明几种与生活方式有关的疾病及其危险因素的流行率和发病率发生了长期变化。因此,这项研究有助于阐明与生活方式有关的疾病的预防策略。该队列的研究工作正在进行中,将为改善人类健康和寿命提供更多数据。
The Hisayama Study is a population-based prospective cohort study designed to evaluate the risk factors for lifestyle-related diseases, such as stroke, coronary heart disease, hypertension, diabetes, and dementia, in a general Japanese population. The prospective follow-up surveys have been conducted in subjects aged 40 or older since 1961. Notable characteristics of this study include its high participation rate (70–80% of all residents aged 40 or older), high follow-up rate (99% or over), and high autopsy rate (approximately 75% of deceased cases). The Hisayama Study has provided valuable evidence of secular change in the prevalence and incidence of several lifestyle-related disease and their risk factors. The study has thereby contributed to elucidation of the preventive strategies for lifestyle-related disease. Research efforts in this cohort are ongoing and will provide additional data for the improvement of human health and longevity.