Relation between troponin T and the risk of subsequent cardiac events in unstable coronary artery disease
Relation between troponin T and the risk of subsequent cardiac events in unstable coronary artery disease
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DOI：
10.1161/01.cir.93.9.1651
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发表时间：
1996-05-01
期刊：
影响因子：
37.8
通讯作者：
Wallentin, L
中科院分区：
文献类型：
--
作者：
Lindahl, B;Venge, P;Wallentin, L
背景：早期风险评估对不稳定性冠状动脉疾病（即不稳定性心绞痛或非Q波心肌梗死）患者非常重要。以前的一些小型研究表明，不稳定型心绞痛和肌钙蛋白T（tn-T）升高的患者有更严重的短期和长期的疾病。在这项研究中，评估了tn-T的预后价值，并与其他早期可用的风险指标进行了比较。方法和结果参与低分子量肝素治疗不稳定冠状动脉疾病随机研究的976名患者在指数发作后接受了5个月的随访。心脏事件的风险随着最初24小时内获得的最大tn-T水平的增加而增加。最低的五分之一（
Background Early risk assessment is important in patients with unstable coronary artery disease, ie, unstable angina or non-Q-wave myocardial infarction. Some previous small studies have indicated that patients with unstable angina and elevation of troponin T (tn-T) have worse short-term and longterm prognoses. In this study, the prognostic value of tn-T was evaluated and compared with other early available risk indicators.Methods and Results Nine hundred seventy-six patients participating in a randomized study of low-molecular-weight heparin in unstable coronary artery disease were followed for 5 months after the index episode. The risk of cardiac events increased with increasing maximal levels of tn-T obtained in the initial 24 hours. The lowest quintile (