Antimicrobial activity of home disinfectants and natural products against potential human pathogens
Antimicrobial activity of home disinfectants and natural products against potential human pathogens
复制标题
DOI：
10.1086/501694
复制
发表时间：
2000-01-01
影响因子：
4.5
通讯作者：
Weber, DJ
中科院分区：
文献类型：
--
作者：
Rutala, WA;Barbee, SL;Weber, DJ
目的：评估两种天然产品的功效（醋，小苏打）和常见的商业消毒剂（Vesphene IIse，TBQ，Clorox，Lysol消毒喷雾，Lysol抗菌厨房清洁剂，Mr. Clean Ultra，乙醇）设计用于家庭或机构使用，对抗潜在的人类病原体，包括选定的耐药性细菌。设计：定量悬浮试验用于评估暴露30秒和5分钟后选定消毒剂的效力。活性评估针对金黄色葡萄球菌、猪霍乱沙门氏菌、大肠杆菌O 157：H7和铜绿假单胞菌。选择的消毒剂也进行了测试，对脊髓灰质炎病毒，万古霉素敏感和耐药的肠球菌物种，和甲氧西林敏感和耐药的金黄色葡萄球菌。结果：以下化合物表现出优异的抗菌活性（>5.8-8.2 log（10）减少）在两个消毒时间：TBQ，Vesphene，Clorox，乙醇，和来苏抗菌厨房清洁剂。Mr. Clean消除了4到>6个日志。和来苏消毒剂在两个暴露时间下的病原微生物相似于4 log（10）。消除醋
OBJECTIVE: To assess the efficacy of both natural products (vinegar, baking soda) and common commercial disinfectants (Vesphene IIse, TBQ, Clorox, Lysol Disinfectant Spray, Lysol Antibacterial Kitchen Cleaner, Mr. Clean Ultra, ethanol) designed for home or institutional use against potential human pathogens, including selected antibiotic-resistant bacteria.DESIGN: A quantitative suspension test was used to assess the efficacy of selected disinfectants following exposure times of 30 seconds and 5 minutes. Activity was assessed against Staphylococcus aureus, Salmonella choleraesuis, Escherichia coli O157:H7, and Pseudomonas aeruginosa. Selected disinfectants were also tested against poliovirus, vancomycin-susceptible and -resistant Enterococcus species, and methicillin-susceptible and -resistant S aureus.RESULTS: The following compounds demonstrated excellent antimicrobial activity (>5.8-8.2 log(10) reduction) at both expo-sure times: TBQ, Vesphene, Clorox, ethanol, and Lysol Antibacterial Kitchen Cleaner. Mr. Clean eliminated 4 to >6 logs,. and Lysol Disinfectant similar to 4 logs(10) of pathogenic microorganisms at both exposure times. Vinegar eliminated