Vaccinia virus complement control protein ameliorates hyperacute xenorejection by inhibiting xenoantibody binding.
Vaccinia virus complement control protein ameliorates hyperacute xenorejection by inhibiting xenoantibody binding.
复制标题
痘苗病毒补体控制蛋白通过抑制异种抗体结合来改善超急性异种排斥。
DOI：
10.1016/s0041-1345(02)03692-8
复制
发表时间：
2002
影响因子：
0.9
通讯作者：
Kotwal,GJ
中科院分区：
文献类型：
--
作者：
Anderson,JB;Smith,SA;vanWijk,R;Chien,S;Kotwal,GJ
痘病毒补体控制蛋白上保守的表面暴露 K/RXK/R 基序和净正电荷可作为假定的肝素结合位点，有助于抑制与人内皮细胞的分子相互作用：一种逃避宿主防御的新机制。
Conserved surface-exposed K/RXK/R motifs and net positive charge on poxvirus complement control proteins serve as putative heparin binding sites and contribute to inhibition of molecular interactions with human endothelial cells: a novel mechanism for evasion of host defense.