Alternate routes of administration and risk for HIV among prescription opioid abusers.
Alternate routes of administration and risk for HIV among prescription opioid abusers.
复制标题
处方阿片类药物滥用者的替代给药途径和艾滋病毒风险。
DOI：
10.1080/10550887.2011.609805
复制
发表时间：
2011
影响因子：
2.3
通讯作者：
Cicero,TheodoreJ
中科院分区：
文献类型：
--
作者：
Surratt,Hilary;Kurtz,StevenP;Cicero,TheodoreJ
给药途径是处方药滥用的不良健康后果的重要因素。目前的研究检查了大量处方阿片类药物滥用者中与非口服给药途径相关的特征，并探讨了针头相关的人类免疫缺陷病毒（HIV）风险行为。在这项研究中，791名阿片类药物滥用者完成了一次性结构化访谈，包括非法和处方药物滥用的完整历史以及药物给药途径。最常见的药丸使用方法是口服（91%），其次是鼻内（53.1%），注射（23.8%）和吸烟（14.5%）。最年轻的处方阿片类药物滥用者，年龄在18-24岁之间，使用替代给药途径和重复使用非无菌注射针头的几率明显更高。应当为年轻的处方类阿片注射者制定艾滋病毒预防方案。
Route of administration is an important contributor to the adverse health consequences of prescription medication abuse. The current study examines characteristics associated with non-oral routes of administration among a large sample of prescription opioid abusers and explores needle-related human immunodeficiency virus (HIV) risk behaviors as well. In the study, 791 opioid abusers completed a one-time structured interview, including complete histories of illicit and prescription drug abuse and route of drug administration. The most common method of pill use was oral (91%), followed by intranasal (53.1%), injection (23.8%), and smoking (14.5%). The youngest prescription opioid abusers, ages 18–24, displayed significantly higher odds of using alternate routes of administration and of reusing nonsterile needles for injection. HIV prevention programming should be developed for young prescription opioid injectors.