Combined use of the intravascular blood-pool agent, gadomer, and carbon dioxide: a novel type of double-contrast magnetic resonance angiography (MRA).
Combined use of the intravascular blood-pool agent, gadomer, and carbon dioxide: a novel type of double-contrast magnetic resonance angiography (MRA).
复制标题
血管内血池剂、gadomer 和二氧化碳的联合使用:一种新型双对比磁共振血管造影 (MRA)。
DOI:
10.1002/jmri.20304
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发表时间:
2005
期刊:
影响因子:
--
通讯作者:
Wacker,FrankK
中科院分区:
文献类型:
--
作者:
Maes,RobbertM;Lewin,JonathanS;Duerk,JeffreyL;Wacker,FrankK
PurposeTo evaluate the combined use of carbon dioxide (CO2) and a gadolinium‐based blood‐pool agent for magnetic resonance angiography (MRA).Materials and MethodsAfter an initial intravenous injection of the blood‐pool agent Gadomer (Schering AG, Germany), repeated transcatheter CO2injections were performed in the aorta and the renal arteries of two fully‐anesthetized pigs. Real‐time images were acquired using a true fast imaging with steady‐state precession (FISP) sequence.ResultsDuring the CO2injections, the Gadomer‐enhanced blood was totally replaced, resulting in an immediate, temporary, total signal loss in the vessel lumen. Susceptibility artifacts during the injections or catheter manipulations rarely occurred.ConclusionDue to T1‐shortening, the circulating blood‐pool agent prevents flow artifacts during catheter manipulations because the steady‐state is reached much earlier. Therefore, this double‐contrast MRA method improves catheter conspicuity and might be helpful for guiding and controlling intravascular procedures during interventional MRI. J. Magn. Reson. Imaging 2005;21:645–649. © 2005 Wiley‐Liss, Inc.