An Unprecedented Tandem Annulation of omega-Azido-1-alkynes with Diaryliodonium Salts: A Facile Synthesis of Polycyclic Quinolines
An Unprecedented Tandem Annulation of omega-Azido-1-alkynes with Diaryliodonium Salts: A Facile Synthesis of Polycyclic Quinolines
复制标题
omega-叠氮基-1-炔烃与二芳基碘鎓盐前所未有的串联环化：多环喹啉的简便合成
作者：
Junjie Chen;Chao Chen;Jing Chen;Hongpeng Gao;Hongmei Qu
多取代喹啉是通过ω-叠氮基-1-炔与作为C2-结构单元的二芳基碘鎓盐的级联成环反应合成的。该反应在Cu（I）催化剂的作用下进行，操作简便，反应条件温和，收率高。
Polysubstituted quinolines are synthesized through an unprecedented cascade annulation of ω-azido-1-alkynes with diaryliodonium salts, which serve as C2-building blocks. The reaction proceeds smoothly and is catalyzed by Cu(I) catalysts to give various quinolines in good isolated yields with simple operation under mild conditions.