Visible-Light-Induced Charge Transfer Enables Csp3–H Functionalization of Glycine Derivatives: Access to 1,3-Oxazolidines
Visible-Light-Induced Charge Transfer Enables Csp3–H Functionalization of Glycine Derivatives: Access to 1,3-Oxazolidines
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可见光诱导电荷转移实现甘氨酸衍生物的 C-sp3-H 功能化：获得 1,3-恶唑烷
DOI：
10.1021/acs.orglett.0c00234
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发表时间：
2020
期刊：
影响因子：
5.2
通讯作者：
Zhang Yuan
中科院分区：
文献类型：
--
作者：
Yang Xiaorong;Zhu Yin;Xie Zhixiang;Li Ying;Zhang Yuan
公开了甘氨酸衍生物和氧化苯乙烯之间的无光氧化还原催化剂、可见光诱导的需氧氧化[2 + 3]环加成反应，其提供了在温和条件下快速合成1，3-恶唑烷的有效方法。这种光诱导过程是通过甘氨酸衍生物和苄基碘之间形成电子给体-受体复合物来实现的。
A photoredox catalyst free, visible-light-induced aerobic oxidative [2 + 3] cycloaddition reaction between glycine derivatives and styrene oxides has been disclosed that provides an efficient approach for the rapid synthesis of 1,3-oxazolidines under mild conditions. This photoinduced process is enabled by the formation of an electron donor–acceptor complex between glycine derivatives and benzyl iodides.