Avian natural killer cells.
Avian natural killer cells.
复制标题
禽类自然杀伤细胞。
DOI：
10.1007/978-3-642-80057-3_10
复制
发表时间：
1996
影响因子：
--
通讯作者：
Cooper,MD
中科院分区：
文献类型：
--
作者：
Göbel,TW;Chen,CH;Cooper,MD
自然杀伤(NK)细胞代表一种独特的淋巴系。这些细胞最初的功能定义是它们杀死某些病毒感染的细胞和肿瘤细胞的能力(Trin Chieri 1989；Ritzet al.(1988年)。这种独特的功能及其进化上的保守性导致了NK细胞被归类为天然免疫系统的一部分。最近，对NK细胞的重新关注使人们对NK细胞的表型、细胞因子的分泌和反应性、发育起源、功能以及介导细胞毒作用的受体有了更好的了解(Morettaet al.(1994年)。
Natural Killer (NK) cells represent a distinct lymphoid lineage. These cells were initially defined functionally by their ability to kill certain virally infected cells and tumor cells (reviewed inTrinchieri1989;Ritzet al. 1988). This unique function and its evolutionary conservation led to the classification of NK cells as part of the innate immune system. Recently, renewed interest in NK cells has lead to better understanding of NK cell phenotype, cytokine secretion and reactivity, developmental origin, functional capabilities, as well as the receptors mediating cytotoxicity (Morettaet al. 1994).