Prevalence and Effect of Problematic Spasticity After Traumatic Spinal Cord Injury

Prevalence and Effect of Problematic Spasticity After Traumatic Spinal Cord Injury
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创伤性脊髓损伤后问题痉挛的发生率和影响

DOI:
10.1016/j.apmr.2016.09.124
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发表时间:
2017-06-01
影响因子:
4.3
通讯作者:
Mills, Patricia B.
Mills, Patricia B.
中科院分区:
医学1区
文献类型:
--
作者:
Holtz, Kaila A.;Lipson, Rachel;Mills, Patricia B.

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目的:评估创伤性脊髓损伤(SCI)后痉挛的发生率和影响。设计:Rick Hansen脊髓损伤登记(RHSCIR)的前瞻性队列研究和住院患者病历的回顾。背景:第四创伤中心、康复中心和社区环境。参与者:2005年3月1日至2014年3月31日期间有创伤性脊髓损伤的个人(N=860),符合纳入条件。干预:不适用。主要结果问卷:问卷(宾夕法尼亚痉挛频率量表,脊髓损伤健康)和抗痉挛药物的使用。结果:在465名患者中,社区出院时痉挛的患病率为65%,问题痉挛(定义为服用抗痉挛药物出院)的患病率为35%。有问题的痉挛与颈胸神经学水平和损伤严重程度相关(P
Objective: To evaluate the prevalence and effect of spasticity after traumatic spinal cord injury (SCI).Design: Prospective cohort study of the Rick Hansen Spinal Cord Injury Registry (RHSCIR) and retrospective review of inpatient medical charts.Setting: Quaternary trauma center, rehabilitation center, and community settings.Participants: Individuals (N=860) with a traumatic SCI between March 1, 2005, and March 31, 2014, prospectively enrolled in the Vancouver site RHSCIR were eligible for inclusion.Interventions: Not applicable.Main Outcome Measures: Questionnaires (Penn Spasm Frequency Scale, Spinal Cord Injury Health Questionnaire) and antispasticity medication use.Results: In 465 patients, the prevalence of spasticity at community discharge was 65%, and the prevalence of problematic spasticity (defined as discharged on antispasticity medication) was 35%. Problematic spasticity was associated with cervicothoracic neurologic level and injury severity (P