Occasions for laughter and dementia risk: Findings from a six-year cohort study
Occasions for laughter and dementia risk: Findings from a six-year cohort study
复制标题
笑的场合和痴呆风险：六年队列研究的结果
DOI：
10.1111/ggi.14371
复制
发表时间：
2023
影响因子：
3.3
通讯作者：
Iso H.
中科院分区：
文献类型：
--
作者：
Wang Y;Shirai K;Ohira T;Hirosaki M;Kondo N;Takeuchi K;Yamaguchi C;Tamada Y;Kondo K;Cadar D;Iso H.
目的目前，几乎没有证据表明笑和痴呆症的风险之间的关系，因为笑主要是一种社会行为，我们的目的是检查各种场合的笑和痴呆症的风险之间的关联在日本老年人。方法我们利用6年的随访数据，从日本老年学评估研究，包括12 165名年龄在65岁或以上的独立老年人。笑的场合使用问卷进行评估，而痴呆症则使用日本长期护理保险系统的标准化痴呆量表进行诊断。结果高笑与低笑组痴呆发病率的多变量危险比为0.84（95%CI：0.72- 0.98，P <0.001）。在女性中，笑的场合越多，患痴呆症的风险越低0.78（95%CI：0.63- 0.96，P <0.001），但在男性中不太明显，仅在中等年龄组中有显著相关性。在与朋友交谈时大笑，与子女或孙辈交流，听收音机主要与降低risk.ConclusionA更大的各种笑声场合在个人和社会设置与痴呆症的风险降低。老年老年国际2022; 22：392-398。
AimCurrently, there is little evidence on the relationship between laughter and the risk of dementia, and since laughter is mainly a social behavior, we aimed to examine the association between various occasions for laughter and the risk of dementia in Japanese older adults.MethodsWe draw upon 6‐year follow‐up data from the Japan Gerontological Evaluation Study, including 12 165 independent older adults aged 65 years or over. Occasions for laughter were assessed using a questionnaire, while dementia was diagnosed using the standardized dementia scale of the long‐term care insurance system in Japan. Cox proportional hazards models were estimated, yielding hazard ratios and 95% confidence intervals (CIs).ResultsThe multivariable hazard ratio of dementia incidence for all participants in the groups for high versus low variety of occasions for laughter was 0.84 (95% CI: 0.72–0.98,Pfor trend <0.001). A greater variety of occasions for laughter was associated with a lower risk of dementia 0.78 (95% CI: 0.63–0.96,Pfor trend <0.001) among women, but was less pronounced for men, with significant associations only for the medium group. Laughing during conversations with friends, communicating with children or grandchildren, and listening to the radio were primarily associated with decreased risk.ConclusionA greater variety of laughter occasions in individual and social settings was associated with a reduced risk of dementia.Geriatr Gerontol Int 2022; 22: 392–398.