The Morphologic Universe of Melanocytic Nevi
The Morphologic Universe of Melanocytic Nevi
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DOI：
10.1016/j.sder.2009.06.005
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发表时间：
2009-09-01
影响因子：
--
通讯作者：
Argenziano, Giuseppe
中科院分区：
文献类型：
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作者：
Zalaudek, Iris;Manzo, Manuela;Argenziano, Giuseppe
不同类型的痣确实存在与其流行病学、形态、进化和相关黑色素瘤风险有关。皮肤镜检查的引入打开了痣形态学领域的新维度，使临床医生能够观察肉眼无法看到的痣内的颜色和结构。由于这些颜色和结构中的大多数都与明确的组织病理学相关性相对应，因此皮肤镜检查使临床医生能够更准确地预测组织病理学诊断，从而提高其临床诊断的准确性。除了诊断影响之外，利用皮肤镜和数字皮肤镜随访对数千个痣进行体内观察，为人们对痣的演变和影响痣模式的因素开辟了新的认识。因此，提出了新的痣分类，将痣分为以下七类：（1）球状/鹅卵石痣，（2）网状痣，（3）星爆痣，（4）均质蓝痣，（5）特殊身体部位的痣，（6）具有特殊特征的痣，以及（7）无法分类的黑素细胞增殖。本文概述了痣的形态分类以及影响痣模式的因素。 Semin Cutan Med Surg 28:149-156 (C) 2009 Elsevier Inc. 保留所有权利。
Different types of nevi do exist in relation to their epidemiology, morphology, evolution, and associated melanoma risk. The introduction of dermoscopy opened a new dimension of the morphologic universe of nevi and allowed clinicians to observe colors and structures within nevi that are otherwise not visible to the unaided eye. Because most of these colors and structures correspond to well-defined histopathologic correlates, dermoscopy enables clinicians to date to more precisely predict the histopathology diagnosis and thereby improve on their clinical diagnostic accuracy. Besides the diagnostic impact, the in vivo observation of thousands of nevi using dermoscopy and digital dermoscopic follow-up has opened new understanding about the evolution of nevi and factors influencing the nevus pattern. In consequence, a new nevus classification has been proposed, subdividing nevi into 7 categories, which are as follows: (1) globular/cobblestone nevi, (2) reticular nevi, (3) starburst nevi, (4) homogeneous blue nevi, (5) nevi on special body sites, (6) nevi with special features, and (7) and unclassifiable melanocytic proliferations. This article provides an overview on the morphologic classification of nevi and the factors influencing the nevus pattern. Semin Cutan Med Surg 28:149-156 (C) 2009 Elsevier Inc. All rights reserved.